Indole and isoindole skeletons are pervasive structural moieties in a plethora of biologically active and synthetically useful compounds as well as natural products. In view of the significance of this framework, the development of efficient protocols to access the purely chiral nitrogen‐containing heterocycles has drawn much attention. Among them, the asymmetric transformations based on cyclic imines via organocatalysis strategies have provided an exciting platform from which various nitrogen heterocycles with distinct structural characters were quickly and conveniently prepared with high chemo‐, diastereo‐ and enantioselectivities. This review, organized on the basis of two primary starting materials, summarizes the progress made in the field of organocatalytic asymmetric reactions involving five‐membered cyclic imines and their precursors as masked cyclic imines which usually feature or generate in situ a carbon‐nitrogen double bond embedded in 3H‐indole, 1H‐isoindole and 1,2‐benzisothiazole 1,1‐dioxide ring systems published since the beginning of 2008, including the substrate scope, mechanisms, applications and limitations.

中文翻译：

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涉及吲哚和异吲哚相关杂环中环亚胺部分的有机催化不对称转化

吲哚和异吲哚骨架是大量生物活性和合成有用的化合物以及天然产物中普遍存在的结构部分。鉴于此框架的重要性，开发访问纯手性含氮杂环的有效方案的研究备受关注。其中，基于环亚胺的不对称转化通过有机催化策略提供了一个令人兴奋的平台，通过该平台可以快速，方便地制备具有高化学，非对映和对映选择性的各种具有不同结构特征的氮杂环。这项综述基于两种主要的起始原料，总结了有机催化不对称反应领域中的进展，该反应涉及五元环亚胺及其前体（通常为原位生成或生成碳-氮双键的掩蔽环亚胺）嵌入自2008年初以来发布的3 H-吲哚，1 H-异吲哚和1,2-苯并噻唑1,1-二氧化环系统中，包括底物的范围，机理，应用和限制。