Spectrum of Enterovirus Serotypes Causing Uncomplicated Hand, Foot, and Mouth Disease and Enteroviral Diagnostic Yield of Different Clinical Samples,Clinical Infectious Diseases

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Spectrum of Enterovirus Serotypes Causing Uncomplicated Hand, Foot, and Mouth Disease and Enteroviral Diagnostic Yield of Different Clinical Samples
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2018-04-24 , DOI: 10.1093/cid/ciy341
Lidong Gao ₁ , Gang Zou ₂ , Qiaohong Liao _{3,

4} , Yonghong Zhou ₄ , Fengfeng Liu ₃ , Bingbing Dai ₅ , Jia Liu ₂ , Zhiyong Chen ₅ , Weijia Xing _{3,

6} , Le Yang ₇ , Hong Liang ₈ , Yi Zhang ₉ , Zhenhua Chen ₁₀ , Li Luo ₃ , Qing Li ₁₁ , Kaiwei Luo ₁ , Peng Wu ₁₂ , Xiaowei Mo ₂ , Lili Wang _{2,

4} , Ke Lan _{2,

13} , Peter W Horby ₁₄ , Benjamin J Cowling ₁₂ , Peter Simmonds ₁₅ , Ralf Altmeyer _{2,

16} , H Rogier van Doorn _{15,

17} , Hongjie Yu _{3,

4}

Affiliation

Hunan Provincial Center for Disease Control and Prevention, Changsha, China
Institut Pasteur of Shanghai, Chinese Academy of Sciences, Beijing, China
Division of Infectious Disease, Key Laboratory of Surveillance and Early Warning on Infectious Disease, Chinese Centre for Disease Control and Prevention, Beijing, China
School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Shanghai, China
Anhua County Center for Disease Control and Prevention, Hunan Province, China
School of Public Health, Taishan Medical College, Taian, Shandong Province, China
Anhua People’s Hospital, Hunan Province, China
Anhua Hospital of Traditional Chinese Medicine, Hunan Province, China
Anhua Second People’s Hospital, Hunan Province, China
Chengdu Center for Disease Control and Prevention, Sichuan Province, China
Yiyang Center for Disease Control and Prevention, Hunan Province, China
World Health Organization Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region
State Key Laboratory of Virology, College of Life Sciences, Wuhan University, China
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom
Nuffield Department of Medicine, University of Oxford, United Kingdom
Qingdao Center for Disease Control and Prevention, China
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Hand, foot, and mouth disease (HFMD) represents a substantial disease burden in the Western Pacific region. We investigated the spectrum of causative enteroviruses of HFMD, and evaluated different clinical samples’ diagnostic yield for enteroviruses.

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