当前位置: X-MOL 学术J. Mater. Chem. C › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Dual-emissive gold nanoclusters for label-free and separation-free ratiometric fluorescence sensing of 4-nitrophenol based on the inner filter effect†
Journal of Materials Chemistry C ( IF 6.4 ) Pub Date : 2018-04-19 00:00:00 , DOI: 10.1039/c8tc00448j
Tong Shu 1, 2, 3, 4, 5 , Jianxing Wang 1, 2, 3, 4, 5 , Xiangfang Lin 1, 2, 3, 4, 5 , Ziping Zhou 1, 2, 3, 4, 5 , Feng Liang 6, 7, 8, 9 , Lei Su 1, 2, 3, 4, 5 , Xueji Zhang 1, 2, 3, 4, 5
Affiliation  

Highly sensitive detection of 4-nitrophenol (4-NP), one of the most hazardous and toxic phenols, has been highly sought-after. In this study, we found that 4-NP could selectively quench the 410 nm emission of the dityrosine (diTyr) residues of BSA-protected gold nanoclusters (GNCs@BSA) rather than the conventional red emission of GNCs@BSA via the inner filter effect (IFE). This finding helped us to develop a label-free and separation-free ratiometric fluorescence method for sensing of 4-NP with red emissive GNCs as the endogenous reference for the first time. This ratiometric sensor exhibited rapid response to 4-NP within 1 min. The photoluminescence (PL) intensity ratio of the 410 nm emission of the diTyr residues to the 630 nm emission of the GNCs (F410/F630) showed a linear relationship with 4-NP concentration in the range of 50 to 5000 nM (R2 = 0.991) with a limit of detection (LOD) (S/N = 3) of 13.8 nM (1.9 ng mL−1), remarkably lower than the concentration limit released by the US Environmental Protection Agency (EPA) for drinking water (60 ng mL−1). Also, the ratiometric sensor showed selectivity for 4-NP over other eight common phenol derivatives. Furthermore, the ratiometric sensor was applied to analyze the trace 4-NP spiked in the tap and river water samples and the satisfied results were acquired, showing promising potential of the ratiometric sensor for practical applications.

中文翻译:

双发射金纳米团簇,基于内部滤光效应,可实现4-硝基苯酚的无标记和无分离比率式荧光感测

高度追求检测最危险和有毒的苯酚之一-4-硝基苯酚(4-NP)的高度敏感性。在这项研究中,我们发现4-NP可以选择性地抑制BSA保护的金纳米簇(GNCs @ BSA)的二氢酪氨酸(diTyr)残留物的410 nm发射,而不是通过内部滤镜效应来抑制GNCs @ BSA的传统红色发射(IFE)。这一发现帮助我们首次开发了一种以红色发射的GNC作为内源参照物来检测4-NP的无标记和无分离的比例荧光方法。这种比例式传感器在1分钟内对4-NP表现出快速响应。diTyr残基的410 nm发射与GNC的630 nm发射的光致发光(PL)强度比(F 410 / F630)显示4-NP浓度在50到5000 nM( R 2 = 0.991)范围内的线性关系,检测限(LOD)(S / N = 3)为13.8 nM(1.9 ng mL -1)。 ,明显低于美国环境保护局(EPA)规定的饮用水(60 ng mL -1)浓度极限。同样,比例传感器对4-NP的选择性也优于其他八种常见的苯酚衍生物。此外,该比例传感器被用于分析自来水和河水样品中的痕量4-NP加标,获得了满意的结果,表明该比例传感器在实际应用中具有广阔的前景。
更新日期:2018-04-19
down
wechat
bug