^§ These authors contributed equally to this work.
Published as part of the Special Topic Modern Coupling Approaches and their Strategic Applications in Synthesis

Abstract

A new and efficient method for the synthesis of 1,3,4-oxadiazoles via the annulation of hydrazides with benzene-1,3,5-triyl triformate (TFBen) under metal-free conditions is reported. A broad range of hydrazides were transformed into the corresponding 1,3,4-oxadiazoles in good yields with excellent functional group tolerance.

A new and efficient method for the synthesis of 1,3,4-oxadiazoles via the annulation of hydrazides with benzene-1,3,5-triyl triformate (TFBen) under metal-free conditions is reported. A broad range of hydrazides were transformed into the corresponding 1,3,4-oxadiazoles in good yields with excellent functional group tolerance.

中文翻译：

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在无金属条件下通过肼和苯甲酸1,3,5-三甲苯酯的合成来合成1,3,4-恶二唑

^§这些作者同等贡献这项工作。
作为专题“现代耦合方法及其在综合中的战略应用”的一部分发布

抽象的

报道了一种在无金属条件下通过酰肼与-1,3,5-三甲酸三甲酸苯酯（TFBen）环合反应合成1,3,4-恶二唑的新方法。大量的酰肼以良好的收率和优异的官能团耐受性被转化为相应的1,3,4-恶二唑。

报道了一种在无金属条件下通过酰肼与-1,3,5-三甲酸三甲酸苯酯（TFBen）环合反应合成1,3,4-恶二唑的新方法。大量的酰肼以良好的收率和优异的官能团耐受性被转化为相应的1,3,4-恶二唑。