Chromones and coumarins are privileged scaffolds that are widely distributed in natural products, synthetic building blocks, pharmaceutical agents, and functional materials. Chromones and coumarins have chemically distinct C−H bonds that can be converted into valuable functional groups for the purpose of constructing compounds with diverse pharmacological profiles. Recent advances in the development of methods and an understanding of the innate electronic properties of chromones and coumarins have led to approaches that provide high levels of site‐selectivity. This focus review highlights recent innovative strategies for the efficient modification of these structural frameworks through site‐selective C−H bond functionalizations.

中文翻译：

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色氨酸和香豆素的位点选择性C H键功能化

色酮和香豆素是特有的支架，广泛分布于天然产物，合成构件，药剂和功能材料中。色酮和香豆素具有化学上独特的CH键，可以将其转换成有价值的官能团，以构建具有多种药理学特征的化合物。方法开发的最新进展以及对色酮和香豆素的固有电子性质的理解导致了提供高水平位点选择性的方法。这篇重点综述着重介绍了通过位点选择性CH键功能化对这些结构框架进行有效修饰的最新创新策略。