Natural hydro-low-transition-temperature mixtures (NH-LTTMs) tend to be the most favorable next-generation green solvents for biomass pretreatment, as they are cheap and environmental friendly. The amount of water bound into the NH-LTTMs greatly affected their thermal stability, whereby the highest thermal stability was observed with the water content of 7.6 wt%. It is worth noting that, the highest molar transition energy of NH-LTTMs (47.57 kcal mol⁻¹), which indicated the highest solubility, was optimized with the molar ratio of hydrogen bond donor (HBD)-hydrogen bond acceptor (HBA)-water (2:4:3) at a temperature of 60 °C. Hydrogen bonding networks of the NH-LTTMs, which led to the dissolution of biomass, were confirmed by the alteration in the peaks of the involved bonds and resonance signal to lower field through FTIR and ¹H NMR spectra, respectively. The components evidenced in high-resolution mass spectra of extracted lignin showed its high potential to be valorized into useful fuels and chemicals.

天然水-低过渡温度混合物（NH-LTTM）往往是最便宜的下一代绿色溶剂，适用于生物质预处理，因为它们价格便宜且对环境友好。结合到NH-LTTM中的水量极大地影响了它们的热稳定性，因此在7.6 wt％的水含量下观察到最高的热稳定性。值得注意的是，NH-LTTMs的最高摩尔转变能为（47.57 kcal mol ^-1在60°C的温度下，用氢键供体（HBD）-氢键受体（HBA）-水（2：4：3）的摩尔比优化了指示最高溶解度的）。NH-LTTM的氢键网络导致了生物质的溶解，这分别通过FTIR和¹ H NMR谱图所涉及的键的峰的变化和向低场的共振信号的变化来证实。在提取的木质素的高分辨率质谱图中证明的成分表明，其具有很强的潜力，可以被有价值地转化为有用的燃料和化学物质。