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Identifying peptide sequences that can control the assembly of gold nanostructures†
Molecular Systems Design & Engineering ( IF 3.6 ) Pub Date : 2018-04-11 00:00:00 , DOI: 10.1039/c7me00091j
Hye-Eun Lee 1, 2, 3, 4, 5 , Jaehun Lee 1, 2, 3, 4, 5 , Misong Ju 1, 2, 3, 4, 5 , Hyo-Yong Ahn 1, 2, 3, 4, 5 , Yoon Young Lee 1, 2, 3, 4, 5 , Hyung-Seok Jang 2, 3, 4, 5, 6 , Ki Tae Nam 1, 2, 3, 4, 5
Affiliation  

This study is about how peptide sequences can control the assembly and growth of gold nanomaterials. Two cysteine-containing sequences, YYCYY and glutathione (GSH), have been newly identified as assembly motifs to control the resulting two-dimensional (2D) morphology. Cysteine interacts with gold ions and the gold surface to initiate nucleation and control growth. YYCYY forms a flat, 2D, gold-decorated film and GSH results in twisted, petal-like structures. By conducting a comparative study of these two sequences, the important role of peptide folding in the gold atom assembly process is investigated.

中文翻译:

识别可以控制金纳米结构组装的肽序列

这项研究是关于肽序列如何控制金纳米材料的组装和生长。最近已将两个含半胱氨酸的序列YYCYY和谷胱甘肽(GSH)识别为装配基序,以控制所得的二维(2D)形态。半胱氨酸与金离子和金表面相互作用,以启动成核作用并控制生长。YYCYY形成平坦的2D金色装饰膜,GSH形成扭曲的花瓣状结构。通过对这两个序列进行比较研究,研究了肽折叠在金原子组装过程中的重要作用。
更新日期:2018-04-11
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