Metal-free oxidative coupling of quinoxalin-2(1H)-ones with arylaldehydes leading to 3-acylated quinoxalin-2(1H)-ones†,Organic & Biomolecular Chemistry

当前位置： X-MOL 学术 › Org. Biomol. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Metal-free oxidative coupling of quinoxalin-2(1H)-ones with arylaldehydes leading to 3-acylated quinoxalin-2(1H)-ones†
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2018-04-10 00:00:00 , DOI: 10.1039/c8ob00206a
Jin-Wei Yuan _{1,

2,

3,

4} , Jun-Hao Fu _{1,

2,

3,

4} , Shuai-Nan Liu _{1,

2,

3,

4} , Yong-Mei Xiao _{1,

2,

3,

4} , Pu Mao _{1,

2,

3,

4} , Ling-Bo Qu _{3,

4,

5,

6}

Affiliation

A facile TBHP-mediated direct oxidative coupling of quinoxalin-2(1H)-ones with arylaldehydes has been developed under metal-free conditions. This method provided a convenient and efficient approach to various 3-acylated quinoxalin-2(1H)-ones from readily available starting materials with excellent regioselectivity. This reaction proceeded efficiently under mild conditions over a broad range of substrates and with functional group tolerance.

中文翻译：

喹喔啉-2（1 H）-one与芳醛的无金属氧化偶联导致3-酰化的喹喔啉-2（1 H）-one †

在无金属条件下，已经开发了一种简便的TBHP介导的喹喔啉-2（1 H）-one与芳醛的直接氧化偶联。该方法提供了一种方便有效的方法，可从易于获得的起始材料中以优异的区域选择性对各种3-酰化的喹喔啉-2（1 H）-酮进行分离。该反应在温和条件下在宽范围的底物上且在具有官能团耐受性的情况下有效地进行。

更新日期：2018-04-10

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>