In this Review, we consider the story of cocaine from its humble origins in South America to its status as one of the most abused substances in 21st century society. The synthesis and biosynthesis of cocaine are discussed, as well as its pharmacokinetics, metabolism, pharmacology, and importance in modern neuroscience and molecular imaging.

中文翻译：

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化学神经科学中的黑暗经典：可卡因

在这篇评论中，我们考虑了可卡因的故事，从可卡因在南美的卑微起源到其在21世纪社会中最易滥用的物质之一。讨论了可卡因的合成和生物合成，及其药代动力学，新陈代谢，药理学及其在现代神经科学和分子成像中的重要性。