A new convenient procedure for the synthesis of oxazolines from tosylmethyl isocyanide (TosMIC) and aldehydes using imidazole as an efficient catalyst has been reported. The synthesized oxazolines were able to be protected from the oxidation by using just water both as a good solvent and anti oxidant. All the synthesized compounds show good anti biofilm activity against staphylococcus epidermidis.

中文翻译：

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由TosMIC和水中的醛合成恶唑啉的新颖便捷的氧化控制程序-抗生物膜活性

已经报道了使用咪唑作为有效催化剂由甲苯磺酰基甲基异氰化物（TosMIC）和醛合成恶唑啉的新便捷方法。仅使用水作为良溶剂和抗氧化剂，就可以保护合成的恶唑啉免受氧化。所有合成的化合物均对表皮葡萄球菌具有良好的抗生物膜活性。