The aim of this study was to investigate the feasibility of utilizing different lignocellulosic hydrolysates with various hexose versus pentose (H:P) ratios to produce lactic acid (LA) from Bacillus coagulans IPE 22 by fermentations with single and mixed sugar. In single sugar utilization, glucose tended to promote LA production, and xylose preferred to enhance cell growth. In mixed sugar utilization, glucose and pentose were consumed simultaneously when glucose concentration was lower than 20 g/L, and almost the same concentration of LA (50 g/L) was obtained regardless of the differences of H:P values. Finally, LA production from corn cob hydrolysates (CCH) contained 60 g/L mixed sugar verified the mechanisms found in the fermentations with simulated sugar mixture. Comparing with single glucose utilization, CCH utilization was faster and the yield of LA was not significantly affected. Therefore, the great potential of producing LA with lignocellulosic materials by B. coagulans was proved.

这项研究的目的是研究利用具有不同的己糖对戊糖（H：P）比率的不同木质纤维素水解物从凝结芽孢杆菌生产乳酸（LA）的可行性。通过单糖和混合糖发酵获得IPE 22。在单糖利用中，葡萄糖倾向于促进LA的产生，而木糖则倾向于增强细胞的生长。在混合糖利用中，当葡萄糖浓度低于20 g / L时，葡萄糖和戊糖同时消耗，无论H：P值如何，都获得几乎相同的LA（50 g / L）浓度。最后，由玉米芯水解物（CCH）产生的LA包含60 g / L混合糖，验证了在模拟糖混合物发酵中发现的机制。与单糖利用率相比，CCH利用率更快，LA的产量也没有受到明显影响。因此，证明了凝结芽孢杆菌利用木质纤维素材料生产LA的巨大潜力。