Cell-based drug delivery systems offer the prospect of biocompatibility, large-loading capacity, longin vivolifespan, and active targeting of diseased sites. However, these opportunities are offset by an array of challenges, including safeguarding the integrity of the drug cargo and the cellular host, as well as ensuring that drug release occurs at the appropriate time and place. Emerging strategies that address these, and related, issues, are described herein.

中文翻译：

---

细胞半机械人：药物输送革命的绝境

基于细胞的药物递送系统提供了生物相容性，大负载能力，更长的体内寿命以及主动靶向患病部位的前景。但是，这些机遇被一系列挑战所抵消，其中包括维护药品和细胞宿主的完整性，以及确保在适当的时间和地点释放药物。本文描述了解决这些及相关问题的新兴策略。