A simple tandem Wittig reaction-reductive decarboxylation route is established for the synthesis of indoles from commercially available o-nitrobenzaldehydes and a stable phosphorane. The method allows access to indoles in a very fast manner without involving any metal or expensive reagents or inert atmosphere. Also 2-substituted indoles are obtained which forms an important core of many biological active compounds.

中文翻译：

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Tandem Wittig –还原环化脱羧方法，用于合成吲哚和2-取代的吲哚

建立了一种简单的串联维蒂希反应-还原脱羧路线，用于从可商购的邻硝基苯甲醛和稳定的磷烷合成吲哚。该方法允许以非常快速的方式接触吲哚，而无需涉及任何金属或昂贵的试剂或惰性气氛。还获得2-取代的吲哚，其形成许多生物活性化合物的重要核心。