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Update on the main use of biomaterials and techniques associated with tissue engineering
Drug Discovery Today ( IF 7.4 ) Pub Date : 2018-03-30 , DOI: 10.1016/j.drudis.2018.03.013
Daniela Steffens , Daikelly I. Braghirolli , Natasha Maurmann , Patricia Pranke

Regenerative medicine involves the study of cells, signaling cues and biomatrices to restore normal function of tissues and organs. To develop the matrices for use in tissue engineering there are three main groups of biomaterials: (i) naturally derived materials; (ii) synthetic polymers; and (iii) decellularized organ or tissue scaffolds. These biomaterials, in various forms such as hydrogels, nanofibers and 3D scaffolds, among others, have been employed for different tissue regeneration purposes, with several techniques involved in their production, including rapid prototyping, tissue decellularization and electrospinning. In this review, the main topics of hydrogels, 3D printing and electrospun scaffolds, other biomaterials and decellularization and recellularization will be discussed.



中文翻译:

有关与组织工程相关的生物材料和技术的主要用途的最新信息

再生医学涉及细胞,信号提示和生物基质的研究,以恢复组织和器官的正常功能。为了开发用于组织工程的基质,主要有三类生物材料:(i)天然来源的材料;(ii)合成聚合物;(iii)去细胞的器官或组织支架。这些生物材料,例如水凝胶,纳米纤维和3D支架等各种形式,已用于不同的组织再生目的,其生产涉及多种技术,包括快速成型,组织脱细胞和静电纺丝。在这篇综述中,将讨论水凝胶,3D打印和电纺支架,其他生物材料以及脱细胞和再细胞化的主要主题。

更新日期:2018-03-30
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