Two convergent syntheses for compound 1 are described that apply Buchwald–Hartwig coupling as the key step. This development work provides a direct comparison of the coupling results from different coupling partners and illustrates that more efficiency can be achieved by selecting the right coupling partners.

中文翻译：

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在开发用于合成c-Kit抑制剂的Buchwald-Hartwig联轴器中例证首选联轴器的预测

描述了化合物1的两个收敛合成，这些合成应用Buchwald-Hartwig偶联作为关键步骤。这项开发工作提供了来自不同耦合伙伴的耦合结果的直接比较，并说明通过选择正确的耦合伙伴可以实现更高的效率。