Allium species have been widely used for culinary and medicinal purposes. This study attempts for the first time to investigate into the enzyme inhibitory potential of different plant parts of Allium scorodoprasum L. subsp. rotundum (L.) Stearn, also known as wild garlic or leek in Turkey. The antioxidant and enzyme inhibitory potential of the flower, stem, and bulb extracts of A. scorodoprasum were assessed using in vitro bio-assays. The phenolic composition of the different plant parts was also established. The flower extract, having high phenolic content (27.69 mg GAEg extract), showed potent antioxidant activity as a metal chelating agent (22.27 mg EDTAE/g extract), radical scavenger (34.83 and 66.02 mg trolox equivalent (TE)/g extract, for 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) assays, respectively) and reducing agent (90.53 mg TE/g extract, for the cupric reducing antioxidant capacity assay). Besides, the flower extract was a potent inhibitor of butyrylcholinesterase (3.16 mg galantamine equivalent (GALAE)/g extract) and tyrosinase (55.21 mg kojic acid equivalent/g extract). The flower extract was rich in rosmarinic acid. In silico studies revealed that rosmarinic acid established several hydrogen bonds and π–π interactions in the enzymatic cavity of butyrylcholinesterase. On the other hand, the stem extract of A. scorodoprasum showed inhibitory action against acetylcholinesterase (2.17 mg GALAE/g extract) and α-amylase (0.55 mmol acarbose equivalent/g extract). Interestingly, we noted that the bulb extract of A. scorodoprasum, inferior in phenolic compounds, showed the least activity. These results suggest that the different plant parts of A. scorodoprasum possessed different biological activities and might be used as a medicinal food plants for specific therapeutic applications.

葱属物种已被广泛用于烹饪和医学目的。这项研究首次尝试调查葱蒜亚种（Allium scorodoprasum L. subsp。）不同植物部分的酶抑制潜力。圆形（L.）Stearn，在土耳其也称为野蒜或韭菜。使用体外方法评估了芥菜花，茎和鳞茎提取物的抗氧化和酶抑制潜力生物测定。还确定了植物不同部位的酚类成分。花提取物具有较高的酚含量（27.69 mg GAEg提取物），对于金属螯合剂（22.27 mg EDTAE / g提取物），自由基清除剂（34.83和66.02 mg trolox当量（TE）/ g提取物）具有强大的抗氧化活性。 2,2-二苯基-1-吡咯肼基和2,2'-叠氮基双（3-乙基苯并噻唑啉-6-磺酸）测定）和还原剂（90.53 mg TE / g提取物，用于铜还原抗氧化能力测定）。此外，花提取物是丁酰胆碱酯酶（3.16mg加兰他敏当量（GALAE）/ g提取物）和酪氨酸酶（55.21mg曲酸当量/ g提取物）的有效抑制剂。花提取物富含迷迭香酸。在计算机上研究表明，迷迭香酸在丁酰胆碱酯酶的酶腔中建立了几个氢键和π-π相互作用。另一方面，A.scorodoprasum的茎提取物显示出对乙酰胆碱酯酶（2.17mg GALAE / g提取物）和α-淀粉酶（0.55mmol阿卡波糖当量/ g提取物）的抑制作用。有趣的是，我们注意到，劣于酚类化合物的A. scorodoprasum鳞茎提取物显示出最低的活性。这些结果表明，鞘孢曲霉的不同植物部分具有不同的生物学活性，并且可以用作用于特定治疗应用的药用食用植物。