Frankincense gum resin secreted from Boswellia papyrifera was analysed by comprehensive 2D gas chromatography hyphenated with accurate mass time-of-flight mass spectrometry (GC×GC−accTOFMS). Direct multiple injection experiments with stepwise isothermal temperature programming were then performed to construct isovolatility curves for reference alkane series in GC×GC. This provides access to calculation of second dimensional retention indices (²I). More than 500 peaks were detected and 220 compounds mainly comprising monoterpenes, sesquiterpenes, diterpenes and oxygenated forms of these compounds were identified according to their ¹I, ²I and accurate mass data. The study demonstrates the capability of GC×GC−accTOFMS with retention data on two separate column phases, as an approach for improved component identification. A greater number of identified and/or tentatively identified terpenoids in this traditional Chinese medicine allow for a more comprehensive coverage of the volatile composition of frankincense.

通过精确的飞行时间质谱联用（GC×GC-accTOFMS）联用的二维二维气相色谱分析了乳香乳香分泌的乳香树胶树脂。然后进行逐步等温编程的直接多次进样实验，以建立GC×GC中参考烷烃系列的等容曲线。这提供了对第二维保留指数（² I）的计算的访问。检测到500多个峰，并根据其¹ I，² I鉴定了220种主要由单萜，倍半萜，双萜和这些化合物的氧化形式组成的化合物准确的质量数据。该研究证明了GC×GC-accTOFMS具有在两个单独的色谱柱相上保留数据的能力，作为改进的组分鉴定方法。在这种传统中药中，大量已鉴定和/或初步鉴定的萜类化合物可以更全面地覆盖乳香的挥发性成分。