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Dehydrogenative etherification homocoupling of heterocyclic N-oxides
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2018-03-26 , DOI: 10.1016/j.tetlet.2018.03.071
Dong Zhang , Kai Qiao , Xin Yuan , Mingwei Zheng , Zheng Fang , Li Wan , Kai Guo

A novel approach was developed for the dehydrogenative etherification homocoupling of heterocyclic N-oxides in the presence of silver oxide and PyBroP. Various substrates were well tolerated and the desired products were obtained in moderate to good yields. Generally, this reaction features excellent functional group compatibility, broad substrate scope and good regioselectivity.



中文翻译:

杂环N-氧化物的脱氢醚化均偶联。

开发了一种新颖的方法,用于在氧化银和PyBroP存在下杂环N-氧化物的脱氢醚化均偶联。各种底物具有良好的耐受性,并以中等至良好的产率获得了所需的产物。通常,该反应具有优异的官能团相容性,广泛的底物范围和良好的区域选择性。

更新日期:2018-03-26
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