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Dihalogen and Solvent-Free Preparation of syn-Bimane
Synlett ( IF 2 ) Pub Date : 2018-03-21 , DOI: 10.1055/s-0036-1591964
Flavio Grynszpan 1 , Ishita Neogi 1 , Partha Das 1
Affiliation  

Fluorescent bimanes are low molecular weight and low toxicity molecules with applications ranging from biology to LASER dyes. The widespread use of these molecular probes has presumably been stalled by the hazards involved in their current synthetic preparation which involve handling of dangerous halogens like chlorine (gas) and bromine (liq.). The accessibility achieved by the simple and safe dihalogen and solvent-free methodologies described here open the floodgates to additional future practical applications of bimanes.

中文翻译:

合成双烷的无卤无溶剂制备

荧光 bimanes 是低分子量和低毒性分子,其应用范围从生物学到激光染料。这些分子探针的广泛使用可能由于其当前合成制备中涉及的危险而停滞,这些危险涉及处理危险的卤素,如氯(气体)和溴(液体)。此处描述的简单且安全的二卤化物和无溶剂方法所实现的可及性为 bimanes 的其他未来实际应用打开了闸门。
更新日期:2018-03-21
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