Dehalogenation of 5-halogenopyrimidine derivatives in boiling pure water was accomplished in high yields. The substrate and pure water are the only two reaction components in this process. Dehalogenation takes place in the absence of any catalysts, additives, basic, or acidic conditions, introducing water as a potential dehalogenation reagent.

中文翻译：

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纯水诱导的2,4-二叔-氨基-6-取代的5-卤代嘧啶的脱卤

5-卤代嘧啶衍生物在沸腾的纯水中脱卤以高收率完成。底物和纯水是该过程中仅有的两个反应组分。在没有任何催化剂，添加剂，碱性或酸性条件下进行脱卤作用，将水引入作为潜在的脱卤剂。