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Nanopharmaceuticals for wound healing – Lost in translation?
Advanced Drug Delivery Reviews ( IF 16.1 ) Pub Date : 2018-03-19 , DOI: 10.1016/j.addr.2018.03.005
Mukul Ashtikar , Matthias G. Wacker

Today, many of the newly developed pharmaceuticals and medical devices take advantage of nanotechnology and with a rising incidence of chronic diseases such as diabetes and cardiovascular disease, the number of patients afflicted globally with non-healing wounds is growing. This has created a requirement for improved therapies and wound care. However, converting the strategies applied in early research into new products is still challenging. Many of them fail to comply with the market requirements. This review discusses the legal and scientific challenges in the design of nanomedicines for wound healing. Are they lost in translation or is there a new generation of therapeutics in the pipeline?



中文翻译:

用于伤口愈合的纳米药物–翻译失败了吗?

如今,许多新开发的药物和医疗设备都利用了纳米技术,并且随着诸如糖尿病和心血管疾病等慢性疾病的发病率不断上升,全球范围内因未愈合的伤口而受苦的患者人数正在增加。这就提出了改进疗法和伤口护理的要求。但是,将早期研究中应用的策略转换为新产品仍然具有挑战性。他们中的许多人不符合市场要求。这篇综述讨论了用于伤口愈合的纳米药物设计中的法律和科学挑战。他们是在翻译中迷失了方向吗,还是正在准备新一代的治疗方法?

更新日期:2018-03-19
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