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Folate decorated hollow spheres of microporous organic networks as drug delivery materials†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-03-19 00:00:00 , DOI: 10.1039/c8cc01240g
June Young Jang 1, 2, 3, 4 , Huu Thuy Trang Duong 2, 3, 4, 5, 6 , Sang Moon Lee 4, 7, 8 , Hae Jin Kim 4, 7, 8 , Yoon-Joo Ko 4, 9, 10, 11, 12 , Ji Hoon Jeong 2, 3, 4, 6, 13 , Doo Sung Lee 2, 3, 4, 5, 6 , Thavasyappan Thambi 2, 3, 4, 5, 6 , Seung Uk Son 1, 2, 3, 4
Affiliation  

Hollow and microporous organic network spheres decorated with folic acids (H-MON-FA) were prepared using silica templates by the Sonogashira coupling of organic building blocks and successive post-synthetic modifications. The drug (DOX) delivery performance of H-MON-FA to cancer cells was studied.

中文翻译:

叶酸修饰微孔有机网络的空心球作为药物输送材料

通过有机建筑构件的Sonogashira偶联和连续的后合成修饰,使用二氧化硅模板制备了用叶酸(H-MON-FA)装饰的空心和微孔有机网络球体。研究了H-MON-FA对癌细胞的药物(DOX)传递性能。
更新日期:2018-03-19
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