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Probabilistic risk assessment of exposure to fluoride in most consumed brands of tea in the Middle East
Food and Chemical Toxicology ( IF 4.3 ) Pub Date : 2018-03-19 , DOI: 10.1016/j.fct.2018.03.023
Mohammad Miri , Amit Bhatnagar , Yousef Mahdavi , Leila Basiri , Alireza Nakhaei , Rasoul Khosravi , Hadi Eslami , Seyed Mehdi Ghasemi , Davoud Balarak , Ahad Alizadeh , Amir Mohammadi , Zahra Derakhshan , Reza Ali Fallahzadeh , Mahmoud Taghavi

The aim of this study was to evaluate the fluoride concentration in seven most consumed brands of tea in the Middle East which was imported to Iran through Zabol County. In the present study, the health risk of exposure to fluoride was estimated using a probabilistic approach. Monte Carlo simulation and sensitivity analysis were applied to quantify uncertainties in risk estimation. The highest mean and 95th percentile of chronic daily intake (CDI) was observed for children group. Iranian tea and Kenya tea had maximum CDI and target hazard quotient (THQ) values among studied brands of tea which followed by Green tea, Taksetare tea, Ceylan tea, Red tea, and White tea. These result indicated that there were significant risks of exposure to fluoride in most of studied brands of tea for children (THQ>1). Sensitivity analysis showed that fluoride concentration and daily intake were the most influential variables in three exposed populations. In conclusion, the fluoride concentration in some studied brands of tea is high and it put children at risk risks of exposure to fluoride.



中文翻译:

中东大多数消费品牌茶中暴露于氟化物的概率风险评估

这项研究的目的是评估通过Zabol县进口到伊朗的中东七个最消耗茶品牌中的氟化物浓度。在本研究中,使用概率方法估计了暴露于氟化物的健康风险。蒙特卡罗模拟和敏感性分析用于量化风险估计中的不确定性。儿童组的慢性每日摄入量(CDI)最高,最高为95%。在研究的茶品牌中,伊朗茶和肯尼亚茶的CDI和目标危害商(THQ)值最高,其次是绿茶,塔克塞塔雷茶,锡兰茶,红茶和白茶。这些结果表明,在大多数研究过的儿童茶品牌中,暴露于氟化物的风险很大(THQ> 1)。敏感性分析表明,在三个暴露人群中,氟化物浓度和每日摄入量是影响最大的变量。总而言之,某些研究茶品牌中的氟化物浓度很高,这使儿童处于暴露于氟化物的风险中。

更新日期:2018-03-19
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