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Improving thermal control of capillary electrophoresis with mass spectrometry and capacitively coupled contactless conductivity detection by using 3D printed cartridges
Talanta ( IF 6.1 ) Pub Date : 2018-03-16 , DOI: 10.1016/j.talanta.2018.03.052
Kelliton José Mendonça Francisco , Claudimir Lucio do Lago

A 3D-printed cartridge was developed to improve the interface between a capillary electrophoresis instrument and a mass spectrometer. The thermostated airflow from the CE was guided to the entrance of the electrospray source keeping as much as possible the silica capillary in a proper Joule-heating dissipation environment. Hollow 3D-printed walls made of ABS covered by a 0.2 mm thick copper foil on the inner side were used. The cartridge also allows including up to two capacitively coupled contactless conductivity detectors (C4Ds). Experiments about the separation of monoethyl carbonate (a thermally unstable species) shows that the peak area obtained with the original cartridge is only 21% of the value obtained with the 3D-printed cartridge, which demonstrates the improvement in heat dissipation.



中文翻译:

通过使用3D打印墨盒,通过质谱和电容耦合非接触电导率检测来改善毛细管电泳的热控制

开发了3D打印墨盒,以改善毛细管电泳仪和质谱仪之间的界面。来自CE的恒温气流被引导至电喷雾源的入口,并在适当的焦耳热耗散环境中尽可能多地保持二氧化硅毛细管。使用由ABS制成的空心3D打印墙,在其内侧覆盖有0.2 mm厚的铜箔。该滤芯还可以包括最多两个电容耦合的非接触式电导率检测器(C 4 Ds)。关于碳酸单乙酯(一种热不稳定物质)分离的实验表明,使用原始墨盒获得的峰面积仅为使用3D打印墨盒获得的峰面积的21%,这表明散热得到了改善。

更新日期:2018-03-16
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