We introduce a mild and efficient avenue to induce the folding of single chain polymer nanoparticles (SCNPs) using visible light. The versatility of the method is based on three folding mechanisms exploiting tetrazole chemistry, i.e., nitrile imine-mediated tetrazole-ene cycloaddition (NITEC), nitrile imine carboxylic acid ligation (NICAL) as well as nitrile imine self-dimerization. To our knowledge, this visible light driven approach is the to-date mildest avenue to fold single polymer chains into compact particles using light.

中文翻译：

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用可见光折叠聚合物链†

我们介绍一种温和而有效的途径，以使用可见光诱导单链聚合物纳米颗粒（SCNPs）的折叠。该方法的多功能性基于利用四唑化学的三种折叠机制，即腈亚胺介导的四唑-烯环加成（NITEC），腈亚胺羧酸连接（NICAL）以及腈亚胺自二聚化。据我们所知，这种可见光驱动方法是迄今为止使用光将单个聚合物链折叠成致密颗粒的最温和的途径。