Metals can pose hazards to marine species and can adversely affect structures and functions of communities of marine species. However, little is known about how structural properties of metal atoms combined with current geographical and climatic conditions affect their toxic potencies. A mathematical model, based on quantitative structure–activity relationships and species sensitivity distributions (QSAR-SSD) was developed by use of acute toxicities of six metals (Cd, Cr, Cu, Hg, Ni, and Zn) to eight marine species and accessory environmental conditions. The model was then used to predict toxicities of 31 metals and metalloids and then to investigate relationships between acute water quality criteria (WQC) and environmental conditions in coastal marine environments. The model was also used to predict WQC in the coastal areas of different countries. Given global climate change, the QSAR-SSD model allows development of WQC for metals that will be protective of marine ecosystems under various conditions related to changes in global climate. This approach could be of enormous benefit in delivering an evidence-based approach to support regulatory decision making in management of metal and metalloids in marine waters.

中文翻译：

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预测全球沿海海洋环境中金属和类金属毒性的模型

金属可能对海洋生物造成危害，并可能对海洋生物群落的结构和功能产生不利影响。但是，关于金属原子的结构特性与当前地理和气候条件如何影响其毒性的作用鲜为人知。通过使用六种金属（Cd，Cr，Cu，Hg，Ni和Zn）对八种海洋物种及其附件的急性毒性，建立了基于定量构效关系和物种敏感度分布（QSAR-SSD）的数学模型。环境条件。然后，该模型用于预测31种金属和准金属的毒性，然后研究急性水质标准（WQC）与沿海海洋环境中环境条件之间的关系。该模型还用于预测不同国家沿海地区的WQC。考虑到全球气候变化，QSAR-SSD模型允许开发用于金属的WQC，以在与全球气候变化有关的各种条件下保护海洋生态系统。这种方法在提供基于证据的方法来支持管理海水中金属和准金属的监管决策方面可能会带来巨大的好处。