Abstract The aim of this work was to synthesize polymeric microparticles as carriers for nitrogen, phosphorus, and potassium (NPK fertilizer) for agricultural applications, using polyglycerol (PG) to improve the synthesis procedure. Multivariate experimental designs were employed to obtain a satisfactory synthesis. The desirability function identified the best conditions for preparation of the microparticles as being 100.00 mg of poly(e-caprolactone) (PCL), 825.00 mg of PG, 9.25 mL of chloroform, and 0.9% w/v of polyvinyl alcohol (PVA). This resulted in average encapsulation rates of 94.23% for N, 99.80% for P, and 65.00% for K. The profile of release from the microparticles was according to diffusion following Fick’s Law. These observations confirmed the capacity of the proposed microparticles to sustain a continuous and prolonged release of NPK for the purpose of plant fertilization.

中文翻译：

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用于农业应用中 npk 缓释的聚合物微粒

摘要 这项工作的目的是合成聚合物微粒作为农业应用的氮、磷和钾 (NPK 肥料) 的载体，使用聚甘油 (PG) 改进合成程序。采用多变量实验设计以获得令人满意的合成。合意性函数确定了制备微粒的最佳条件为 100.00 mg 聚（e-己内酯）（PCL）、825.00 mg PG、9.25 mL 氯仿和 0.9% w/v 聚乙烯醇（PVA）。这导致 N 的平均包封率为 94.23%，P 的平均包封率为 99.80%，K 的平均包封率为 65.00%。微粒的释放曲线是根据 Fick 定律的扩散。