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Solvent‐Induced Crystal Polymorphism as Studied by Pyroelectric Measurements and Impedance Spectroscopy: Alcohols as Tailor‐Made Inhibitors of α‐Glycine
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2018-03-12 , DOI: 10.1002/anie.201802722
Elena Meirzadeh 1 , Shiri Dishon 1 , Isabelle Weissbuch 1 , David Ehre 1 , Meir Lahav 1 , Igor Lubomirsky 1
Affiliation  

Minute amounts of methanol are selectively incorporated within the bulk of α‐glycine crystals, as detected by pyroelectric measurements and impedance spectroscopy. In their Communication (DOI: 10.1002/anie.201800741), E. Meirzadeh, M. Lahav, I. Lubomirsky, and co‐workers show that pronounced differences are observed between the dielectric properties of α‐glycine crystals grown in aqueous solution or alcohol/water mixtures. These differences provide a rational explanation as to why alcohols induce the formation of the metastable β‐polymorph.


中文翻译:

通过热释电测量和阻抗谱研究的溶剂诱导的晶体多态性:醇作为α-甘氨酸的特制抑制剂

通过热电测量和阻抗谱检测,少量的甲醇选择性地掺入了大部分α-甘氨酸晶体中。E.Meirzadeh,M.Lahav,I.Lubomirsky及其同事在其交流中(DOI:10.1002 / anie.201800741)发现,在水溶液或酒精中生长的α-甘氨酸晶体的介电​​性质之间存在明显差异/水混合物。这些差异为酒精为什么会诱导亚稳态β-多晶型物的形成提供了合理的解释。
更新日期:2018-03-21
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