Background

Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin.

Methodology/Principal findings

A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006–2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32–176 days).

Conclusions/Significance

This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment.

中文翻译：

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2006-2016年在贝宁治疗的尼日利亚布鲁里溃疡82例系列报告

背景

尼日利亚是西非布鲁里溃疡 (BU) 流行国家之一，但直到最近才制定控制计划。因此，BU 患者经常在邻近的贝宁获得治疗服务，那里建立了专门的卫生设施，为 BU 患者提供免费治疗。本研究旨在描述在贝宁四个治疗中心中的三个治疗的尼日利亚病例的流行病学、临床、生物学和治疗特征。

方法论/主要发现

2006 年至 2016 年期间，在贝宁的三个中心治疗了来自尼日利亚的 82 例 BU 病例，并进行了回顾性描述。这些患者中的大多数来自与贝宁接壤的奥贡州和拉各斯州。大多数病例被诊断为溃疡性病变（80.5%）和WHO III类病变（82.9%）；97.5% 的患者在中位住院 46 天后痊愈（四分位距 [IQR]：32-176 天）。

结论/意义

这份报告增加了对尼日利亚 BU 流行病学的了解，希望该计划将加强旨在早期发现和治疗病例的努力。