Abstract The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine.

中文翻译：

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用于心脏组织工程的聚（甘油癸二酸酯）/聚（丁二酸丁二酯-二亚油酸丁二醇酯）共混物的动态机械表征通过平冲纳米压痕

摘要 通过动态平面冲压纳米压痕在 1 至 45 Hz 的频率范围内研究了用于心脏组织贴片的聚（甘油癸二酸酯）（PGS）和聚（丁二酸二亚油酸丁二醇酯）（PBS-DLA）共聚物的聚合物共混物的粘弹性。 . 发现储能模量与测试频率的相关性很弱，最低值为 1 Hz，这对应于通常的心率。更重要的是，发现在 40 到 70 重量％之间改变 PGS 含量允许在 11 到 39 MPa 之间调整共混物的储能模量。纳米压痕方法的可靠性通过使用拉伸试验机对较厚的 PBS-DLA 样品进行参考动态机械测量来验证。