In this paper we present a wirelessly powered array of 128 centrifugo-pneumatic valves that can be thermally actuated on demand during spinning. The valves can either be triggered by a predefined protocol, wireless signal transmission via Bluetooth, or in response to a sensor monitoring a parameter like the temperature, or homogeneity of the dispersion. Upon activation of a resistive heater, a low-melting membrane (Parafilm™) is removed to vent an entrapped gas pocket, thus letting the incoming liquid wet an intermediate dissolvable film and thereby open the valve. The proposed system allows up to 12 heaters to be activated in parallel, with a response time below 3 s, potentially resulting in 128 actuated valves in under 30 s. We demonstrate, with three examples of common and standard procedures, how the proposed technology could become a powerful tool for implementing diagnostic assays on Lab-on-a-Disc. First, we implement wireless actuation of 64 valves during rotation in a freely programmable sequence, or upon user input in real time. Then, we show a closed-loop centrifugal flow control sequence for which the state of mixing of reagents, evaluated from stroboscopically recorded images, triggers the opening of the valves. In our last experiment, valving and closed-loop control are used to facilitate centrifugal processing of whole blood.

在本文中，我们介绍了一个由128个离心气动阀组成的无线阵列，可以在纺纱期间按需进行热驱动。阀门既可以通过预定义的协议，通过蓝牙的无线信号传输来触发，也可以响应传感器监控的参数（例如温度或分散体的均质性）来触发。激活电阻加热器后，将低熔点膜（Parafilm™）移除以排出残留的气穴，从而使进入的液体润湿中间可溶解的膜，从而打开阀门。所提出的系统允许并行激活多达12个加热器，响应时间低于3 s，有可能在30 s内导致128个致动阀。我们通过三个通用和标准程序示例进行演示，拟议的技术如何成为在光盘实验室上实施诊断分析的有力工具。首先，我们在旋转过程中以可自由编程的顺序或在用户实时输入后实现64个阀门的无线致动。然后，我们显示了一个闭环离心流控制序列，根据频闪记录的图像评估试剂的混合状态会触发阀门的打开。在我们的最后一个实验中，使用阀门和闭环控制来促进全血的离心处理。从频闪记录的图像中进行评估，会触发阀门的打开。在我们的最后一个实验中，使用阀门和闭环控制来促进全血的离心处理。从频闪记录的图像中进行评估，会触发阀门的打开。在我们的最后一个实验中，使用阀门和闭环控制来促进全血的离心处理。