The site-selective copper-catalyzed three-component coupling reaction of electron-deficient heterocycles, Se powder and aryl iodides is disclosed. The established methodology provides an efficient and practical pathway to access 2-arylselenated heterocycles via copper-catalyzed double C–Se bond formation. This transformation features the use of elemental Se as the selenating reagent, a cost-effective catalytic system, and the late-stage selenation of bioactive compounds.

中文翻译：

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硒与芳基碘化物和杂环的铜催化二芳基化†

公开了缺电子杂环，Se粉和碘代芳基的位点选择性铜催化的三组分偶联反应。既定的方法学提供了一种有效且实用的途径，可通过铜催化的双C-Se双键形成来访问2-芳基硒化杂环。这种转变的特征是使用元素硒作为硒化试剂，具有成本效益的催化系统以及生物活性化合物的后期硒化。