当前位置: X-MOL 学术Toxicol. Res. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Anticancer, antimicrobial, and analgesic activities of spider venoms
Toxicology Research ( IF 2.1 ) Pub Date : 2018-03-08 00:00:00 , DOI: 10.1039/c8tx00022k
Hassan M. Akef 1
Affiliation  

Spider venoms are complex mixtures composed of a variety of compounds, including salts, small organic molecules, peptides, and proteins. But, the venom of a few species is dangerous to humans. High levels of chemical diversity make spider venoms attractive subjects for chemical prospecting. Many spider venom components show potential activity against a wide range of human diseases. However, the development of novel venom-derived therapeutics requires an understanding of their mechanisms of action. This review will highlight the structures, activities and the possible mechanisms of action of spider venoms and their components against cancer, microbial infections, and pain.

中文翻译:

蜘蛛毒液的抗癌,抗菌和镇痛作用

蜘蛛毒液是由多种化合物组成的复杂混合物,包括盐,有机小分子,肽和蛋白质。但是,少数物种的毒液对人类是危险的。高水平的化学多样性使蜘蛛毒液成为进行化学勘探的诱人对象。许多蜘蛛毒成分显示出对多种人类疾病的潜在活性。但是,新型毒液疗法的发展需要了解它们的作用机理。这篇综述将重点介绍蜘蛛毒液的结构,活性以及可能的作用机理,以及其成分针对癌症,微生物感染和疼痛的作用。
更新日期:2018-03-08
down
wechat
bug