A novel analytical method based on the coupling of dispersive micro-solid phase extraction (D-μSPE) and supramolecular solvent microextraction (SUPRAS-ME) has been developed for the extraction and preconcentration of ultra-trace copper in water and food samples. In the hyphenated D-μSPE-SUPRAS-ME, initially copper ions were extracted from a large volume of aqueous sample (100 mL) into a 30 mg aluminum fumarate (Al-Fu) metal–organic framework. After the desorption of the analytes from the sorbent using THF, the desorption solution was used in the SUPRAS-ME method as a dispersant solution. In this way, higher enrichment factors could be achieved. Different parameters were optimized for obtaining maximum extraction efficiency of copper from various samples (water and food sampls). Under the optimal conditions, an enrichment factor in aqueous solution of 280 was obtained. The calibration curve was linear in the range of 0.5–15 ng mL⁻¹ with correlation coefficients ≥0.99. The intra-day reproducibility of the method was satisfactory with relative standard deviations less than or equal to 6.5%. Moreover, the detection limit and limit of quantification were 0.2 ng mL⁻¹ and 0.5 ng mL⁻¹, respectively.

中文翻译：

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基于金属-有机骨架的微固相萃取与超分子溶剂微萃取结合，用于测定水和食品样品中的铜

开发了一种基于分散微固相萃取（D-μSPE）和超分子溶剂微萃取（SUPRAS-ME）耦合的新型分析方法，用于水和食品样品中超痕量铜的萃取和预富集。在连接后的D-μSPE-SUPRAS-ME中，最初将铜离子从大量的水性样品（100 mL）中提取到30 mg的富马酸铝（Al-Fu）金属-有机框架中。在使用THF从吸附剂中解吸分析物之后，该解吸溶液在SUPRAS-ME方法中用作分散剂溶液。以这种方式，可以实现更高的富集因子。优化了不同的参数，以从各种样品（水和食物样品）中获得最大的铜提取效率。在最佳条件下 在水溶液中获得的富集因子为280。校准曲线在0.5–15 ng mL范围内呈线性^-1，相关系数≥0.99。该方法的日内重现性令人满意，相对标准偏差小于或等于6.5％。另外，检出限和定量限分别为0.2ngmL ^-1和0.5ngmL ^-1。