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Dispersive solid-phase imprinting of proteins for the production of plastic antibodies†
Chemical Communications ( IF 4.9 ) Pub Date : 2018-03-07 00:00:00 , DOI: 10.1039/c8cc00343b
Jon Ashley 1, 2, 3, 4, 5 , Xiaotong Feng 1, 2, 3, 4, 5 , Arnab Halder 1, 2, 3, 4, 5 , Tongchang Zhou 1, 2, 3, 4, 5 , Yi Sun 1, 2, 3, 4, 5
Affiliation  

We describe a novel dispersive solid-phase imprinting technique for the production of nano-sized molecularly imprinted polymers (nanoMIPs) as plastic antibodies. The template was immobilized on in-house synthesized magnetic microspheres instead of conventional glass beads. As a result, high-affinity and template-free MIPs were produced in higher yields.

中文翻译:

蛋白质的分散固相印记用于生产塑料抗体

我们描述了一种新型的分散固相印迹技术,用于生产作为塑料抗体的纳米级分子印迹聚合物(nanoMIPs)。将模板固定在内部合成的磁性微球上,而不是固定在常规玻璃珠上。结果,以更高的产量产生了高亲和力和无模板的MIP。
更新日期:2018-03-07
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