当前位置: X-MOL 学术Chem. Eur. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Improvement of Photodynamic Activity of Lipid–Membrane‐Incorporated Fullerene Derivative by Combination with a Photo‐Antenna Molecule
Chemistry - A European Journal ( IF 4.3 ) Pub Date : 2018-04-06 , DOI: 10.1002/chem.201800674
Daiki Antoku 1 , Shuhei Satake 1 , Tomoya Mae 1 , Kouta Sugikawa 1 , Hisakage Funabashi 2 , Akio Kuroda 2 , Atsushi Ikeda 1
Affiliation  

The weak absorbance of pristine C60, C70, and fullerene derivatives at wavelengths over 600 nm hampers the use of these molecules as photosensitizers (PSs) for photodynamic therapy (PDT). The coexistence of light‐harvesting antenna molecules with a fullerene derivative in lipid membrane bilayers solved this issue. By controlling the location of the C60 derivative in the lipid membrane, the liposomal dyad system for PDT improved the photodynamic activity via an efficient photoenergy transfer from antenna molecules to the fullerene derivative. The photodynamic activity was found to be much higher than those of dyad systems using pristine C60 and C70.

中文翻译:

结合光触媒分子改善脂膜掺入富勒烯衍生物的光动力活性

原始C 60,C 70和富勒烯衍生物在600 nm以上波长处的弱吸收性妨碍了将这些分子用作光动力疗法(PDT)的光敏剂(PSs)。脂质膜双层中光捕获天线分子与富勒烯衍生物的共存解决了这个问题。通过控制C 60衍生物在脂质膜中的位置,用于PDT的脂质体二聚体系统通过从天线分子到富勒烯衍生物的有效光能转移,改善了光动力活性。发现光动力学活性比使用原始C 60和C 70的二元体系高得多。
更新日期:2018-04-06
down
wechat
bug