-
SARS‐CoV‐2‐infected human airway epithelial cell cultures uniquely lack interferon and immediate early gene responses caused by other coronaviruses Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-04-15 Ying Wang, Melissa Thaler, Clarisse Salgado‐Benvindo, Nathan Ly, Anouk A Leijs, Dennis K Ninaber, Philip M Hansbro, Fia Boedijono, Martijn J van Hemert, Pieter S Hiemstra, Anne M van der Does, Alen Faiz
-
Chitinase 3‐like 1 expression associated with lymphatic metastasis and prognosis in urothelial carcinoma of the bladder Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-04-15 Bo Wang, Ke Chen, Mingchao Gao, Xi Sun, Wang He, Junyu Chen, Wenjuan Yang, Tenghao Yang, Haide Qin, Honglian Ruan, Hao Huang, Tianxin Lin, Jian Huang
-
Chimeric antigen receptor T cells in the fast lane among autoimmune disease therapies Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-04-12 Zhoujie Ding, David Tarlinton
-
CD177 drives the transendothelial migration of Treg cells enriched in human colorectal cancer Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-04-09 Shouyu Ke, Yi Lei, Yixian Guo, Feng Xie, Yimeng Yu, Haigang Geng, Yiqing Zhong, Danhua Xu, Xu Liu, Fengrong Yu, Xiang Xia, Zizhen Zhang, Chunchao Zhu, Wei Ling, Bin Li, Wenyi Zhao
-
Identification of distinct immune signatures in inclusion body myositis by peripheral blood immunophenotyping using machine learning models Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-04-03 Emily McLeish, Anuradha Sooda, Nataliya Slater, Kelly Beer, Ian Cooper, Frank L Mastaglia, Merrilee Needham, Jerome D Coudert
-
Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine‐induced killer cell efficiency in multiple myeloma via the NKG2D pathway Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-25 Jingjing Pu, Amit Sharma, Ting Liu, Jian Hou, Ingo GH Schmidt‐Wolf
-
Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-23 Cui Tu, Irina Buckle, Ingrid Leal Rojas, Gustavo Rodrigues Rossi, David P Sester, Andrew S Moore, Kristen Radford, Camille Guillerey, Fernando Souza‐Fonseca‐Guimaraes
-
CD39 expression defines exhausted CD4+ T cells associated with poor survival and immune evasion in human gastric cancer Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-18 Zhen‐quan Duan, Yu‐xian Li, Yuan Qiu, Yang Shen, Ying Wang, Yuan‐yuan Zhang, Bao‐hang Zhu, Xiao‐hong Yu, Xue‐ling Tan, Weisan Chen, Yuan Zhuang, Ping Cheng, Wei‐jun Zhang, Quan‐ming Zou, Dai‐yuan Ma, Liu‐sheng Peng
-
Graft‐versus‐leukaemia immunity is retained following treatment with post‐transplant cyclophosphamide alone or combined with tocilizumab in humanised mice Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-16 Chloe Sligar, Ellie Reilly, Peter Cuthbertson, Kara L Vine, Katrina M Bird, Amal Elhage, Stephen I Alexander, Ronald Sluyter, Debbie Watson
-
Prediction of intravenous immunoglobulin retreatment in children with Kawasaki disease using models combining lymphocyte subset and cytokine profile in an East Asian cohort Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-13 Chun Zhang, Sun Chen, Yan Bian, Xiaohua Qian, Yurui Liu, Liqing Zhao, Jia Shen, Jiani Song, Peng Zhang, Lun Chen, Limin Jiang
-
Unremitting pro‐inflammatory T‐cell phenotypes, and macrophage activity, following paediatric burn injury Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-03-08 Donna Langley, Kate Zimmermann, Emma Krenske, Giorgio Stefanutti, Roy M Kimble, Andrew JA Holland, Mark W Fear, Fiona M Wood, Tony Kenna, Leila Cuttle
-
Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-29 Ruth A Purcell, L Carissa Aurelia, Robyn Esterbauer, Lilith F Allen, Katherine A Bond, Deborah A Williamson, Janine M Trevillyan, Jason A Trubiano, Jennifer J Juno, Adam K Wheatley, Miles P Davenport, Thi HO Nguyen, Katherine Kedzierska, Stephen J Kent, Kevin John Selva, Amy W Chung
-
High KRT17 expression in tumour budding indicates immunologically ‘hot’ tumour budding and predicts good survival in patients with colorectal cancer Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-29 Wenfeng Liang, Haiqing Jie, Hao Xie, Yebohao Zhou, Wenxin Li, Liang Huang, Zhenxing Liang, Huashan Liu, Xiaobin Zheng, Ziwei Zeng, Liang Kang
-
Phenotypic spectrum in a family with a novel RAC2 p.I21S dominant‐activating mutation Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-26 Louisa Ashby, Lydia Chan, Christine Winterbourn, See‐Tarn Woon, Paula Keating, Raoul Heller, Rohan Ameratunga, Ignatius Chua, Kuang‐Chih Hsiao
-
Whole blood transcriptomics reveals granulocyte colony‐stimulating factor as a mediator of cardiopulmonary bypass‐induced systemic inflammatory response syndrome Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-19 Katherine R Martin, Cristina Gamell, Tsin Yee Tai, Roberto Bonelli, Jacinta Hansen, James Tatoulis, Monther Alhamdoosh, Nicholas Wilson, Ian Wicks
-
Effective γδ T‐cell clinical therapies: current limitations and future perspectives for cancer immunotherapy Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-19 Isabella A Revesz, Paul Joyce, Lisa M Ebert, Clive A Prestidge
-
Whole transcriptome profiling of placental pathobiology in SARS-CoV-2 pregnancies identifies placental dysfunction signatures Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-06 Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado-Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia
-
Infiltrating characteristics and prognostic value of tertiary lymphoid structures in resected gastric neuroendocrine neoplasm patients Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-02-05 Daming Cai, Xingzhou Wang, Heng Yu, Chunhua Bai, Yonghuan Mao, Mengjie Liang, Xuefeng Xia, Song Liu, Meng Wang, Xiaofeng Lu, Junfeng Du, Xiaofei Shen, Wenxian Guan
-
SARS-CoV-2-associated T-cell infiltration in the central nervous system Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-31 Malte Mohme, Christoph Schultheiß, Andras Piffko, Antonia Fitzek, Lisa Paschold, Benjamin Thiele, Klaus Püschel, Markus Glatzel, Manfred Westphal, Katrin Lamszus, Jakob Matschke, Mascha Binder
-
γδ T cells mediate robust anti-HIV functions during antiretroviral therapy regardless of immune checkpoint expression Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-29 Kirsty R Field, Kathleen M Wragg, Stephen J Kent, Wen Shi Lee, Jennifer A Juno
-
Multi-omics integration reveals a nonlinear signature that precedes progression of lung fibrosis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-24 Céline Pattaroni, Christina Begka, Bailey Cardwell, Jade Jaffar, Matthew Macowan, Nicola L Harris, Glen P Westall, Benjamin J Marsland
-
A phase II study to evaluate the safety and efficacy of anlotinib combined with toripalimab for advanced biliary tract cancer Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-12 Mingzhen Zhou, Yuncheng Jin, Sihui Zhu, Chen Xu, Lin Li, Baorui Liu, Jie Shen
-
Graft CD8 T-cell-based risk system predicts survival in antithymocyte globulin-based myeloablative haploidentical peripheral blood stem cell transplantation Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-12 Panpan Zhu, Luxin Yang, Yibo Wu, Jimin Shi, Xiaoyu Lai, Lizhen Liu, Yishan Ye, Jian Yu, Yanmin Zhao, Xiaolin Yuan, Huarui Fu, Zhen Cai, He Huang, Yi Luo
-
Cellular models in autoinflammatory disease research Clin. Transl. Immunol. (IF 5.8) Pub Date : 2024-01-11 Başak Şen, Banu Balcı-Peynircioğlu
-
CD14 down-modulation as a real-time biomarker in Kawasaki disease Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-12-30 Yutaro Inada, Motoshi Sonoda, Yumi Mizuno, Kenichiro Yamamura, Yoshitomo Motomura, Aoba Takuma, Kenji Murata, Kenji Furuno, Junichiro Tezuka, Yasunari Sakai, Shouichi Ohga, Junji Kishimoto, Koki Hosaka, Satomi Sakata, Toshiro Hara
-
Inflammatory cytokines as mediators of retinal endothelial barrier dysfunction in non-infectious uveitis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-12-12 Lisia Barros Ferreira, Keryn A Williams, Giles Best, Cameron D Haydinger, Justine R Smith
-
Enhanced and complementary benefits of a nalfurafine and fingolimod combination to treat immune-driven demyelination Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-12-12 Katharina Robichon, Rabia Bibi, Mackenzie Kiernan, Lisa Denny, Thomas E Prisinzano, Bronwyn M Kivell, Anne Camille La Flamme
-
Elevated BMI reduces the humoral response to SARS-CoV-2 infection Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-12-03 Marcus ZW Tong, Julian DJ Sng, Meagan Carney, Lucy Cooper, Samuel Brown, Katie E Lineburg, Keng Yih Chew, Neve Collins, Kirsten Ignacio, Megan Airey, Lucy Burr, Briony A Joyce, Dhilshan Jayasinghe, Christopher LD McMillan, David A Muller, Anurag Adhikari, Linda A Gallo, Emily S Dorey, Helen L Barrett, Stephanie Gras, Corey Smith, Kim Good-Jacobson, Kirsty R Short
-
Changes in immune cell populations following KappaMab, lenalidomide and low-dose dexamethasone treatment in multiple myeloma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-30 Samuel E Norton, Tiffany Khong, Malarmathy Ramachandran, Andrew J Highton, Kirsten A Ward-Hartstonge, Jake Shortt, Andrew Spencer, Roslyn A Kemp
-
Circulating cytokine and chemokine patterns associated with cytomegalovirus reactivation after stem cell transplantation Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-28 Lauren Stern, Helen M McGuire, Selmir Avdic, Emily Blyth, David Gottlieb, Ellis Patrick, Allison Abendroth, Barry Slobedman
-
The spectrum of B cells in the pathogenesis, diagnosis and therapeutic applications of immunoglobulin G4-related disease Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-28 Qiyuan Hao, Meng Sun, Yanying Liu
-
Plasma SARS-CoV-2 RNA elimination and RAGE kinetics distinguish COVID-19 severity Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-23 Xiaoyan Deng, Pierre Gantner, Julia Forestell, Amélie Pagliuzza, Elsa Brunet-Ratnasingham, Madeleine Durand, Daniel E Kaufmann, Nicolas Chomont, Morgan Craig
-
Improving thymus implantation for congenital athymia with interleukin-7 Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-22 Hyunjung Min, Laura A Valente, Li Xu, Shane M O'Neil, Lauren R Begg, Joanne Kurtzberg, Anthony J Filiano
-
Antibody glycosylation correlates with disease progression in SIV-Mycobacterium tuberculosis coinfected cynomolgus macaques Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-20 Ebene R Haycroft, Timon Damelang, Ester Lopez, Mark A Rodgers, Bruce D Wines, Mark Hogarth, Cassaundra L Ameel, Stephen J Kent, Charles A Scanga, Shelby L O'Connor, Amy W Chung
-
Pretreatment albumin is a prognostic and predictive biomarker for response to atezolizumab across solid tumors Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-08 Jonas Saal, Jörg Ellinger, Manuel Ritter, Peter Brossart, Michael Hölzel, Niklas Klümper, Tobias Bald
-
Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-11-02 Katharine A Kott, Adam S Chan, Stephen T Vernon, Thomas Hansen, Taiyun Kim, Macha de Dreu, Bavani Gunasegaran, Andrew J Murphy, Ellis Patrick, Peter J Psaltis, Stuart M Grieve, Jean Y Yang, Barbara Fazekas de St Groth, Helen M McGuire, Gemma A Figtree
-
Early CRP kinetics to predict long-term efficacy of first-line immune-checkpoint inhibition combination therapies in metastatic renal cell carcinoma: an updated multicentre real-world experience applying different CRP kinetics definitions Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-10-25 Benedikt Hoeh, Cristina Cano Garcia, Severine Banek, Niklas Klümper, Alexander Cox, Jörg Ellinger, Philipp Schmucker, Oliver Hahn, Angelika Mattigk, Friedemann Zengerling, Philippe Becker, Kati Erdmann, Bjoern Thorben Buerk, Luka Flegar, Johannes Huber, Charis Kalogirou, Philip Zeuschner
-
Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-10-04 Jack Polmear, Lauren Hailes, Moshe Olshansky, Maureen Rischmueller, Elan L'Estrange-Stranieri, Anne L Fletcher, Margaret L Hibbs, Vanessa L Bryant, Kim L Good-Jacobson
-
Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe? Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-09-29 Alessia Furgiuele, Frederico C Pereira, Stefano Martini, Franca Marino, Marco Cosentino
-
Autoimmune uveitis in Behçet's disease and Vogt-Koyanagi-Harada disease differ in tissue immune infiltration and T cell clonality Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-09-15 Hao Kang, Hongjian Sun, Yang Yang, Zewen K Tuong, Minglei Shu, Yunbo Wei, Yu Zhang, Di Yu, Yong Tao
Non-infectious uveitis is often secondary to systemic autoimmune diseases, with Behçet's disease (BD) and Vogt-Koyanagi-Harada disease (VKHD) as the two most common causes. Uveitis in BD and VKHD can show similar clinical manifestations, but the underlying immunopathogenesis remains unclear.
-
Individualised adjuvant immunotherapy with neoantigen-reactive T cells for gastric signet-ring cell carcinoma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-09-11 Naiqing Ding, Qin Liu, Juan Du, Jie Shao, Yang Yang, Ju Yang, Fangjun Chen, Lixia Yu, Baorui Liu, Jia Wei
The signet-ring cell carcinoma (SRCC) of the stomach is highly invasive. Patients with stage III gastric SRCC usually experience tumor recurrence within 2 years after radical surgery. Unfortunately, there is no effective treatment to postpone recurrence following adjuvant chemotherapy. Our study aimed to explore the safety and efficacy of neoantigen-reactive T lymphocytes (NRTs) in patients with stage
-
Design, optimisation and standardisation of a high-dimensional spectral flow cytometry workflow assessing T-cell immunophenotype in patients with melanoma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-09-07 Jack M Edwards, Miles C Andrews, Hayley Burridge, Robin Smith, Carole Owens, Mark Edinger, Katherine Pilkington, Juliette Desfrancois, Mark Shackleton, Sashendra Senthi, Menno C van Zelm
Despite the success of immune checkpoint blockade, most metastatic melanoma patients fail to respond to therapy or experience severe toxicity. Assessment of biomarkers and immunophenotypes before or early into treatment will help to understand favourable responses and improve therapeutic outcomes.
-
A unique cytotoxic CD4+ T cell-signature defines critical COVID-19 Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-08-28 Sarah Baird, Caroline L Ashley, Felix Marsh-Wakefield, Sibel Alca, Thomas M Ashhurst, Angela L Ferguson, Hannah Lukeman, Claudio Counoupas, Jeffrey J Post, Pamela Konecny, Adam Bartlett, Marianne Martinello, Rowena A Bull, Andrew Lloyd, Alice Grey, Owen Hutchings, Umaimainthan Palendira, Warwick J Britton, Megan Steain, James A Triccas
SARS-CoV-2 infection causes a spectrum of clinical disease presentation, ranging from asymptomatic to fatal. While neutralising antibody (NAb) responses correlate with protection against symptomatic and severe infection, the contribution of the T-cell response to disease resolution or progression is still unclear. As newly emerging variants of concern have the capacity to partially escape NAb responses
-
Glucocorticoid regulation of the mTORC1 pathway modulates CD4+ T cell responses during infection Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-08-29 Huihui Chen, Zhiwen Liu, Jie Zha, Li Zeng, Runyan Tang, Chengyuan Tang, Juan Cai, Chongqing Tan, Hong Liu, Zheng Dong, Guochun Chen
Conventional glucocorticoid (GC) treatment poses significant risks for opportunistic infections due to its suppressive impact on CD4+ T cells. This study aimed to explore the mechanisms by which GCs modulate the functionality of CD4+ T cells during infection.
-
Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-08-29 John Wen-Cheng Chang, Chien-Jung Huang, Wen-Kuan Huang, Yu-Chao Wang, Jia-Juan Hsieh, Yao-Yu Chang, Yen-Lin Huang, Chia-Ling Wu, Yeh-Han Wang, Shu-Jen Chen, Kien Thiam Tan, Chiao-Ping Chen, Chiao-En Wu
Genomic biomarkers predicting immune checkpoint inhibitor (ICI) treatment outcomes for Asian metastatic melanoma have been rarely reported. This study presents data on next-generation sequencing (NGS) and tumour microenvironment biomarkers in 33 cases.
-
Assessment of antibodies in the upper and lower human respiratory tract at steady state and after respiratory viral infection Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-08-08 Marios Koutsakos, Jackson S Turner, M Cristina Vazquez Guillamet, Daniel Reynolds, Tingting Lei, Derek E Byers, Ali H Ellebedy, Philip A Mudd
There is an increasing appreciation for the need to study mucosal antibody responses in humans. Our aim was to determine the utility of different types of samples from the human respiratory tract, specifically nasopharyngeal (NP) swabs obtained for diagnostic purposes and bronchoalveolar lavage (BAL) obtained in outpatient and inpatient settings.
-
Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD-L1) expression in colorectal carcinoma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-08-02 Tomotaka Ugai, Takashi Shimizu, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Genki Usui, Juha P Väyrynen, Kazuo Okadome, Koichiro Haruki, Naohiko Akimoto, Yohei Masugi, Annacarolina da Silva, Kosuke Mima, Xuehong Zhang, Andrew T Chan, Molin Wang, Wendy S Garrett, Gordon J Freeman, Jeffrey A Meyerhardt, Jonathan A Nowak, Mingyang Song, Marios Giannakis, Shuji Ogino
The CD274 (programmed cell death 1 ligand 1, PD-L1)/PDCD1 (programmed cell death 1, PD-1) immune checkpoint axis is known to regulate the antitumor immune response. Evidence also supports an immunosuppressive effect of Fusobacterium nucleatum. We hypothesised that tumor CD274 overexpression might be inversely associated with abundance of F. nucleatum in colorectal carcinoma.
-
A case of T-cell-Epstein–Barr virus-haemophagocytic lymphohistiocytosis and sustained remission following ruxolitinib therapy Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-07-25 Syed Ali, Sharon Choo, Laine Hosking, Anthony Smith, Tiffany Hughes
Epstein–Barr virus (EBV) is a common cause of secondary haemophagocytic lymphohistiocytosis (HLH). While B cells are reservoirs for EBV, infection within T cells and NK cells in this disease can be difficult to treat.
-
Allogeneic haematopoietic cell transplants as dynamical systems: influence of early-term immune milieu on long-term T-cell recovery Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-07-13 Viktoriya Zelikson, Roy Sabo, Myrna Serrano, Younus Aqeel, Savannah Ward, Taha Al Juhaishi, May Aziz, Elizabeth Krieger, Gary Simmons, Catherine Roberts, Jason Reed, Gregory Buck, Amir Toor
Immune recovery following haematopoietic cell transplantation (HCT) functions as a dynamical system. Reducing the duration of intense immune suppression and augmenting antigen presentation has the potential to optimise T-cell reconstitution, potentially influencing long-term outcomes.
-
Epstein–Barr virus and multiple sclerosis: the dawn of a new age Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-06-27 Tri Giang Phan
-
Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-06-27 Wuji Zhang, Louise C Rowntree, Ramona Muttucumaru, Timon Damelang, Malet Aban, Aeron C Hurt, Maria Auladell, Robyn Esterbauer, Bruce Wines, Mark Hogarth, Stephen J Turner, Adam K Wheatley, Stephen J Kent, Sushrut Patil, Sharon Avery, Orla Morrissey, Amy W Chung, Marios Koutsakos, Thi HO Nguyen, Allen C Cheng, Tom C Kotsimbos, Katherine Kedzierska
-
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-06-22 Callum AH Docherty, Anuruddika J Fernando, Sarah Rosli, Maggie Lam, Roland E Dolle, Manuel A Navia, Ronald Farquhar, Danny La France, Michelle D Tate, Christopher K Murphy, Adriano G Rossi, Ashley Mansell
-
The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-06-17 Ali Afrasiabi, Chantelle Ahlenstiel, Sanjay Swaminathan, Grant P Parnell
-
Released dsDNA-triggered inflammasomes serve as intestinal radioprotective targets Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-06-17 Long Chen, Ziwen Wang, Jie Wu, Quan Yao, Jingjing Peng, Chi Zhang, Hongdan Chen, Yingjie Li, Zhongyong Jiang, Yunsheng Liu, Chunmeng Shi
-
Circulating CXCR5+ natural killer cells are expanded in patients with myasthenia gravis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-05-22 Meng-Ru Ge, Chun-Lin Yang, Tao Li, Tong Du, Peng Zhang, Xiao-Li Li, Ying-Chun Dou, Rui-Sheng Duan
-
Epstein–Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-05-17 Olivia G Thomas, Alan Rickinson, Umaimainthan Palendira
-
Hypoxia-inducible factor-1α regulates the interleukin-6 production by B cells in rheumatoid arthritis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-05-09 Chaofan Fan, Jia Li, Yixuan Li, Yuyang Jin, Jiaqi Feng, Ruru Guo, Xinyu Meng, Dongcheng Gong, Qian Chen, Fang Du, Chunyan Zhang, Liangjing Lu, Jun Deng, Xiao-Xiang Chen
-
CD137 deficiency because of two novel biallelic TNFRSF9 mutations in a patient presenting with severe EBV-associated lymphoproliferative disease Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-05-02 Kefeng Shen, Jiachen Wang, Kuangguo Zhou, Wei Mu, Meilan Zhang, Xinyue Deng, Haodong Cai, Wei Zhang, Wei Huang, Min Xiao
-
The prometastatic relevance of tumor-infiltrating B lymphocytes in laryngeal squamous cell carcinoma Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-04-26 Francesco Missale, Mattia Bugatti, Filippo Marchi, Giulio E Mandelli, Maria Bruni, Giulia Palmerini, Matilde Monti, Anna M Bozzola, Giorgio Arena, Luca Guastini, Maurizio Boggio, Giampiero Parrinello, Giorgio Peretti, William Vermi
-
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis Clin. Transl. Immunol. (IF 5.8) Pub Date : 2023-04-18 Dragana Dragoljevic, Man Kit Sam Lee, Gerard Pernes, Pooranee K Morgan, Cynthia Louis, Waled Shihata, Kevin Huynh, Arina A Kochetkova, Patrick W Bell, Natalie A Mellett, Peter J Meikle, Graeme I Lancaster, Michael J Kraakman, Prabhakara R Nagareddy, Beatriz Y Hanaoka, Ian P Wicks, Andrew J Murphy