Four previously undescribed sucrose diester of aryldihydronaphthalene-type lignans, named echiumins A-D, were isolated from the butanol fraction of Echium angustifolium Mill, in addition to a known compound, trigonotin A, which is reported for the first time from the title plant. The structures of isolated compounds were elucidated using spectroscopic methods such as HRESIMS and 1D and 2D NMR spectroscopy. The isolated compounds displayed strong to weak antitumor activity against HepG2 and MCF7 cancer cell lines, with echiumins A and D showed the most potent activity.

中文翻译：

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来自 Echium angustifolium Mill 的芳基二氢萘型木脂素的蔗糖二酯。及其抗肿瘤活性

四种以前未描述的芳基二氢萘型木脂素的蔗糖二酯，命名为 echiumins AD，从 Echium angustifolium Mill 的丁醇馏分中分离出来，此外还有一种已知化合物，trigonotin A，这是首次从标题植物中报道。使用光谱方法，如 HRESIMS 和 1D 和 2D NMR 光谱阐明了分离化合物的结构。分离出的化合物对 HepG2 和 MCF7 癌细胞系显示出强到弱的抗肿瘤活性，其中 Echiumins A 和 D 显示出最有效的活性。