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A Highly Active Cobalt Catalyst System for Kumada Biaryl Cross-Coupling
Synlett ( IF 2 ) Pub Date : 2018-03-06 , DOI: 10.1055/s-0037-1609337
Wenqin Wu 1 , Hung Duong 1
Affiliation  

A highly active cobalt catalyst system has been developed for the cross-coupling reactions of arylmagnesium reagents and aryl bromides. In the presence of 1 mol% CoCl2, 2 mol% IPr·HCl and 2 mol% NaO t Bu, a wide range of (hetero)biaryls are prepared in 51–99% yields at room temperature within a short reaction time.

中文翻译:

用于熊田联芳交叉偶联的高活性钴催化剂体系

高活性钴催化剂体系已被开发用于芳基镁试剂和芳基溴化物的交叉偶联反应。在 1 mol% CoCl2、2 mol% IPr·HCl 和 2 mol% NaO t Bu 的存在下,在室温下短时间内反应时间可以以 51-99% 的产率制备多种(杂)联芳基化合物。
更新日期:2018-03-06
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