An adsorbent, consisting of silica-coated Fe₃O₄ grafted graphene oxide and β-cyclodextrin (Fe₃O₄@SiO₂/GO/β-CD), which possessed the merits of antioxidation, superparamagnetism, high surface area, high supramolecular recognition and environment friendly, was successfully fabricated. Considering the synergy between β-CD and graphene oxide in adsorption mechanism, the synthesized adsorbent could grasp compounds especially with aromatic structures through π-π interaction, hydrophobic interaction and host-guest inclusion complex forming. Based on the advantages, a magnetic solid phase extraction (MSPE) method for 9 PGRs using Fe₃O₄@SiO₂/GO/β-CD as adsorbents was developed in this study. The characterizations of Fe₃O₄@SiO₂/GO/β-CD were performed on Fourier transform infrared spectrometry (FT-IR), X-ray photoelectron spectroscopy (XPS), CHNS/O elemental analyzer, scanning electron microscopy (SEM) and vibrating sample magnetometry (VSM). Under the optimal MSPE condition, the Fe₃O₄@SiO₂/GO/β-CD exhibited selectivity capability toward 9 PGRs when compared with Fe₃O₄@SiO₂/GO. Meanwhile, the selectivity capability of Fe₃O₄@SiO₂/GO/β-CD was higher than that of Fe₃O₄@SiO₂/GO/α-CD except for 4-FPA. When the developed MSPE procedure was coupled with ultra-high performance liquid chromatography-triple quadrupole linear ion trap mass spectrometry (UHPLC-QTrap-MS/MS) to quantitative analysis of 9 PGRs, linearities ranging from 2 to 50 μg/kg were achieved for 9 PGRs with the correlation coefficients (r²) in the range of 0.9975-0.9999. The limits of detection (LODs) for 9 analytes varied from 0.04 to 0.29 μg/kg. Finally, the proposed technique was applied to analyze PGRs residues in mutiple vegetable samples.

一种由二氧化硅包覆的Fe ₃ O ₄接枝氧化石墨烯和β-环糊精（Fe ₃ O ₄ @SiO ₂ / GO /β-CD）组成的吸附剂，具有抗氧化，超顺磁性，高表面积，超分子高的优点。认可和环境友好，被成功地捏造了。考虑到β-CD和氧化石墨烯在吸附机理上的协同作用，合成的吸附剂可以通过π-π相互作用，疏水相互作用和客体-内含物复合物的形成来抓住具有芳族结构的化合物。基于这些优点，使用Fe ₃ O ₄ @SiO ₂对9种PGR进行磁固相萃取（MSPE）方法在这项研究中开发了/ GO /β-CD作为吸附剂。Fe ₃ O ₄ @SiO ₂ / GO /β-CD的表征通过傅里叶变换红外光谱（FT-IR），X射线光电子能谱（XPS），CHNS / O元素分析仪，扫描电子显微镜（SEM）进行和振动样品磁力计（VSM）。在最佳MSPE条件下，与Fe ₃ O ₄ @SiO ₂ / GO相比，Fe ₃ O ₄ @SiO ₂ / GO /β-CD对9种PGR具有选择性。同时，Fe ₃ O ₄ @SiO ₂ / GO /β-CD的选择性比Fe高。除4-FPA外，₃ O ₄ @SiO ₂ / GO /α-CD。当已开发的MSPE程序与超高效液相色谱-三重四极杆线性离子阱质谱（UHPLC-QTrap-MS / MS）结合用于9种PGR的定量分析时，线性范围为2至50μg/ kg 9个PGR，相关系数（r ²）在0.9975-0.9999范围内。9种分析物的检出限（LOD）在0.04至0.29μg/ kg之间。最后，将所提出的技术用于分析多种蔬菜样品中的PGRs残留。