A simple tool to perform multiple reactions in parallel in batch mode in static segments within a single tube is described. The Segmented Tube Reactor (STR) involves using syringe pumps to load a section of Teflon tubing with solutions of reaction components while forming a preprogrammed gradient of one of the components (e.g., equivalents, concentration) along its length. Simultaneously, a chemically inert spacer is loaded to break the gradient into discrete static segments. Ten or more distinct sets of conditions can be quickly set up in a single experiment. Although the STR is set up in flow mode, reactions occur in batch mode within the tubes, usually by heating the STR for a desired duration. Segments are then individually sampled and analyzed to identify the conditions that provide the best performance. The technology is translatable: the STR was employed to screen for preferred reaction stoichiometries that were then duplicated on larger scale in batch mode in traditional lab equipment.

中文翻译：

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分段管反应器（STR）：一个简单的工具，可在单个管中以批处理模式并行筛选多个反应

描述了一种简单的工具，可以在单个管中的静态段中以批处理模式并行执行多个反应。分段管反应器（STR）涉及使用注射泵在部分特氟隆管中加载反应组分的溶液，同时沿其长度形成组分之一的预编程梯度（例如，当量，浓度）。同时，加载化学惰性的间隔基以将梯度分解为离散的静态片段。可以在一个实验中快速设置十组或更多组不同的条件。尽管将STR设置为流动模式，但通常会通过将STR加热所需的时间，在管内以间歇模式进行反应。然后分别对片段进行采样和分析，以识别提供最佳性能的条件。该技术是可翻译的：