Lerman et al¹ report the increased presence of noncalcified coronary plaques and high-risk plaques in patients with psoriasis in comparison with healthy volunteers and a separately and previously included older at-risk population of hyperlipidemic patients. They concluded that modulation of skin inflammation was associated with a reduced coronary plaque burden.

These findings corroborate previous studies showing increased prevalence of coronary artery disease in patients with psoriasis² and reduced coronary artery disease progression in patients with psoriasis treated with biological agents.³ The results of Lerman et al are in line with a previous report of reduced progression of noncalcified coronary vessel wall volume in patients with psoriasis treated with biological agents.³ However, these studies were performed in patients …

Lerman等[ ^1]报告说，与健康志愿者以及单独且先前包括的高危高脂血症患者相比，牛皮癣患者中非钙化冠状动脉斑块和高危斑块的存在增加。他们得出结论，调节皮肤炎症与减少冠状动脉斑块负担有关。

这些发现证实了先前的研究，这些研究表明，用生物制剂治疗牛皮癣^2的患者冠状动脉疾病的患病率增加，而牛皮癣患者的冠状动脉疾病的进展减少。³ Lerman等人的结果与先前报道的用生物制剂治疗牛皮癣患者的非钙化冠状动脉壁体积的进展减少的报道相符。³然而，这些研究是在患者中进行的……