In this study, water droplets generated using an ultrasonic atomizer at room temperature were replaced with water droplets heated to a high temperature (further denoted as hot water droplets) by an electrical heating steam generator during the preparation of porous membranes via phase inversion to reduce the amount of consumed water and fabrication time. As a result, porous polylactic acid (PLA) membranes were successfully prepared, and their microstructure and physical properties were studied by scanning electron microscopy (SEM), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and differential scanning calorimetry (DSC). Further, the effect of the PLA concentration on the morphology and thermal properties of the produced membranes was investigated. The application of hot water droplets significantly improved the exchange rate between the solvent and non-solvent phases, which increased the average pore diameter. Increasing the PLA concentration decreased the pore diameter, and the produced pores became irregular due to the decrease in the mobility of PLA molecules. At the same time, the higher PLA concentrations also increased the thermal stability and crystallinity of the porous membranes which were fabricated without using any toxic coagulants has and thus could be potentially used in tissue engineering and artificial organ development.

在这项研究中，在通过相转化制备多孔膜的过程中，通过电加热蒸汽发生器将在室温下使用超声雾化器产生的水滴替换为加热到高温的水滴（进一步称为热水水滴），以减少消耗的水量和制造时间。结果，成功制备了多孔聚乳酸（PLA）膜，并通过扫描电子显微镜（SEM），热重分析（TGA），X射线衍射（XRD）和差示扫描量热法（DSC）研究了其微结构和物理性质。 ）。此外，研究了PLA浓度对生产的膜的形态和热性能的影响。水滴的施加显着提高了溶剂相和非溶剂相之间的交换速率，从而增加了平均孔径。增加PLA的浓度会降低孔径，并且由于PLA分子的迁移率降低，产生的孔会变得不规则。同时，较高的PLA浓度也增加了不使用任何有毒凝结剂制成的多孔膜的热稳定性和结晶度，因此可潜在地用于组织工程和人造器官的开发。