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A Small-Molecule Splicing Modulator Targets Spliceosome-Mutant Cells
Cancer Discovery ( IF 28.2 ) Pub Date : 2018-04-01 , DOI: 10.1158/2159-8290.cd-rw2018-038
American Association for Cancer Research

The small molecule H3B-8800 binds to and modulates the SF3b complex to kill spliceosome-mutant cells.



中文翻译:

小分子剪接调节剂靶向剪接突变体细胞。

小分子H3B-8800结合并调节SF3b复合物以杀死剪接体突变细胞。

更新日期:2018-04-02
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