Perfluoroalkyl substances (PFASs) are environmentally persistent chemicals widely used in many consumer products due to water and oil proofing and fire-resistant properties. Several PFASs are recognized as environmental pollutants. This study investigated serum concentrations of 18 different PFASs and their associations with diet and lifestyle variables in 940 adolescents (age 15–19 years) who participated in the Fit Futures 1 study in the Troms arctic district of Norway. Serum concentrations of PFASs were analyzed by ultrahigh pressure liquid chromatography coupled to a triple quadrupole mass spectrometer (UHPLC-MS/MS). The most abundant PFASs in this population were perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexane sulfonate (PFHxS), perfluorononanoate (PFNA) and perfluorodecanoate (PFDA) that were found in 99% of the participants. Perfluoroheptane sulfonate (PFHpS) was found in 98% of the participants. Median concentrations were: PFOS 6.20 ng/mL, PFOA 1.92 ng/mL, PFHxS 0.71 ng/mL, PFNA 0.50 ng/mL, PFDA 0.21 ng/mL and PFHpS 0.15 ng/mL. Median of PFASs sum concentration (∑PFAS) was 10.7 ng/mL, the concentration range was 2.6–200.8 ng/mL. Intake of fat fish, fish liver, seagull eggs, reindeer meat and drinks with sugar were the main dietary predictors of several PFASs. Intake of junk food (pizza, hamburger, sausages) was positively associated with PFNA, intake of canned food was positively associated with PFHxS. Intake of fruits and vegetables, milk products, snacks and candy was not associated with PFASs concentrations. Lean fish intake was positively associated with PFUnDA, but not with other PFASs. There was a positive association of ∑PFAS, PFHxS, PFOA, PFNA and PFDA with chewed tobacco use.

全氟烷基物质（PFAS）由于具有防水防油和耐火特性，因此被广泛用于许多消费产品中，是对环境持久的化学物质。几种全氟辛烷磺酸被认为是环境污染物。这项研究调查了940名青少年（参加挪威Troms北极区的Fit Futures 1研究）的940名青少年（年龄15-19岁）中18种不同PFAS的血清浓度及其与饮食和生活方式变量的关系。PFAS的血清浓度通过与三重四极杆质谱仪（UHPLC-MS / MS）结合的超高压液相色谱法进行分析。该人群中最丰富的PFAS是全氟辛烷磺酸（PFOS），全氟辛酸酯（PFOA），全氟己烷磺酸（PFHxS），在99％的参与者中发现了全氟壬酸（PFNA）和全氟癸酸酯（PFDA）。在98％的参与者中发现了全氟庚烷磺酸盐（PFHpS）。中位数浓度为：PFOS 6.20 ng / mL，PFOA 1.92 ng / mL，PFHxS 0.71 ng / mL，PFNA 0.50 ng / mL，PFDA 0.21 ng / mL和PFHpS 0.15 ng / mL。PFAS总浓度中位数（∑PFAS）为10.7 ng / mL，浓度范围为2.6–200.8 ng / mL。脂肪鱼类，鱼肝，海鸥卵，驯鹿肉和含糖饮料的摄入是几种全氟辛烷磺酸的主要饮食预测指标。垃圾食品（比萨饼，汉堡包，香肠）的摄入量与PFNA正相关，罐头食品的摄入量与PFHxS正相关。水果和蔬菜，奶制品，零食和糖果的摄入与全氟辛烷磺酸的浓度无关。瘦鱼的摄入与PFUnDA呈正相关，但不能与其他PFAS一起使用。∑PFAS，PFHxS，PFOA，PFNA和PFDA与咀嚼型烟草的使用呈正相关。