Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC),International Journal of Epidemiology

当前位置： X-MOL 学术 › Int. J. Epidemiol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)
International Journal of Epidemiology ( IF 7.7 ) Pub Date : 2018-02-27 , DOI: 10.1093/ije/dyy006
Mark A Jenkins _{1,

2} , Aung Ko Win _{1,

2,

3} , Allyson S Templeton ₄ , Maggie S Angelakos ₁ , Daniel D Buchanan _{1,

2,

3,

5} , Michelle Cotterchio ₆ , Jane C Figueiredo _{7,

8} , Stephen N Thibodeau ₉ , John A Baron ₁₀ , John D Potter _{4,

11} , John L Hopper _{1,

2} , Graham Casey ₁₂ , Steven Gallinger ₁₃ , Loic Le Marchand ₁₄ , Noralane M Lindor ₁₅ , Polly A Newcomb _{4,

11} , Robert W Haile ₇ , Dennis Ahnen , Kristen Anton , Julie Arnold , Melyssa Aronson , Kelly Aujard , Bharati Bapat , John Baron , Melissa Barker , Adrian Bickerstaffe , Terrilea Burnett , Iona Cheng , James Church , Timothy Church , Mark Clendenning , Darshana Daftary , Melissa DeRycke , Elizabeth Dicks , Anh Diep , Dave Duggan , Mary Jane Esplen , Douglass Fisher , Samantha Fox , Amy French , Graham Giles , Karen Glanz , Jack Goldblatt , Richard Goldberg , Ellen Goode , William Grady , Cary Greenberg , Jane Green , Roger Green , John Grove , Robert Gryfe , Patricia Harmon , Eric Holowaty , Spring Holter , John Hopper , Louise Keogh , Hyeja Kim , Judy Kirk , Peter Lance , Mercy Laurino , Barbara Leggett , A Joan Levine , Paul Limburg , Jan Lowery , Laurie Lydum , Finlay Macrae , Lisa Madlensky , Karen Makar , Rachel Malen , Judi Maskiell , Pamela McAllister , Ellen McGannon , Gail McKeown-Eyssen , John McLaughlin , Heide Miller-Pakvasa , Gabriela Moslein , Nathalie Nguyen , Sandy Nigon , Patrick Parafrey , Susan Parry , Susan Peterson , Amanda Phipps , Aaron Pollett , Mark Redston , Scott Rogers , Robert Sandler , Sheri Schully , Teresa Selander , Daniella Seminara , Stacey Shiovitz , Kim Siegmund , Thomas Smyrk , Douglas Snazel , Melissa Southey , John Stubbs , Graeme Suthers , Duncan Thomas , Kathy Tucker , Dee West , Michael Woods , Ban Younghusband , Joanne Young ,

Affiliation

Centre for Epidemiology and Biostatistics, University of Melbourne, Parkville, VIC, Australia
University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Parkville, VIC, Australia
Genetic Medicine, Royal Melbourne Hospital, Parkville, VIC, Australia
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Colorectal Oncogenomics Group, University of Melbourne, Parkville, VIC, Australia
Prevention and Cancer Control, Cancer Care Ontario, Toronto, ON, Canada
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Molecular Genetics Laboratory, Mayo Clinic, Rochester, MN, USA
Department of Medicine, University of North Carolina School of Medicine, and Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, NC, USA
School of Public Health, University of Washington, Seattle, WA, USA
Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
University of Hawaii Cancer Center, Honolulu, Hawaii, USA
Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, AZ, USA

Colorectal cancer has long been one of the most frequently diagnosed cancers in the world, with an estimated 1.4 million new cases diagnosed each year (9.8% of worldwide cancer diagnoses) and the cause of 694 000 deaths (8.5% of all worldwide cancer deaths) in 2012.¹ In 1996, as a commitment to reduce morbidity and mortality from this disease, the National Cancer Institute (NCI) of the U.S. National Institutes of Health invited investigators to apply for funding to establish a ‘Cooperative Family Registry for Colorectal Cancer Studies’ (RFA: CA-96-011). The main NIH stated aims were: to collect pedigree information, epidemiological data and related biological specimens from participants with and without colorectal cancer and with and without a family history of the disease, as a resource for interdisciplinary studies on the aetiology of colorectal cancer; and to identify a population at high risk of colorectal cancer that could benefit from preventive strategies. This cohort profile provides an update of the Colon Cancer Family Registry, described in detail in Newcomb et al.²

中文翻译：

队列资料：结肠癌家庭注册队列（CCFRC）

大肠癌长期以来一直是世界上最常被诊断的癌症之一，每年估计诊断出140万新病例（占全球癌症诊断的9.8％），并导致694 000例死亡（占全球所有癌症死亡的8.5％）。在2012年^。1为了减少这种疾病的发病率和死亡率，1996年，美国国立卫生研究院国家癌症研究所（NCI）邀请研究人员申请资助，以建立“结直肠癌研究合作家庭注册机构”（RFA： CA-96-011）。NIH声明的主要目的是：从有或没有大肠癌以及有和没有该疾病家族史的参与者收集家谱信息，流行病学数据和相关生物学标本，作为有关大肠癌病因学的跨学科研究的资源；并确定可以从预防策略中受益的大肠癌高危人群。该队列资料提供了结肠癌家族登记处的更新，在Newcomb等人的文章中有详细描述。^2个

更新日期：2018-02-27

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>