Sepsis is a major cause of illness and death, but it is challenging to diagnose, particularly in the early stages. The global incidence of sepsis is estimated to be around 30 million episodes per year, with a high incidence in neonates and children accounting for around 3 million cases and 1·2 million cases per year, respectively. According to the UK Sepsis Trust, sepsis claims more lives per year in the UK than lung cancer, and more lives than bowel, breast, and prostate cancer combined. Complexity in the diagnosis of sepsis arises from the heterogeneity of this disorder—it can be caused by a wide range of pathogens acting on different organs.

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哭泣的狼：败血症警报周围越来越严重的疲劳

败血症是疾病和死亡的主要原因，但诊断难度很大，尤其是在早期阶段。据估计，全球败血症的发病率约为每年3000万例，新生儿和儿童的高发病率分别约为每年300万例和1·200万例。根据英国脓毒症基金会（Sussis Trust）的数据，脓毒症每年在英国的死亡人数要多于肺癌，并且比肠道癌，乳腺癌和前列腺癌的总和还多。败血症诊断的复杂性源于这种疾病的异质性，它可能是由作用在不同器官上的多种病原体引起的。