A silver/polypyrrole/copper oxide (Ag/PPy/Cu₂O) ternary nanocomposite was prepared by sonochemical and oxidative polymerization simple way, in which Cu₂O was decorated with Ag nanoparticles, and covered by polyprrole (PPy) layer. The as prepared materials was characterized by UV-vis-spectroscopy (UV-vis), FT-IR, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), scanning electron microscopy (SEM) with EDX, high resolution transmission electron microscopy (HR-TEM) and X-ray photoelectron spectroscopy (XPS). Sensing of serotonin (5HT) was evaluated electrocatalyst using polypyrrole/glassy carbon electrode (PPy/GCE), polypyrrole/copper oxide/glassy carbon electrode (PPy/Cu₂O/GCE) and silver/polypyrrole/copper oxide/glassy carbon electrode (Ag/PPy/Cu₂O/GCE). The Ag/PPy/Cu₂O/GCE was electrochemically treated in 0.1MPBS solution through cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The peak current response increases linearly with 5-HT concentration from 0.01 to 250 µmol L^-1 and the detection limit was found to be 0.0124 μmol L^-1. It exhibits high electrocatalytic activity, satisfactory repeatability, stability, fast response and good selectivity against potentially interfering species, which suggests its potential in the development of sensitive, selective, easy-operation and low-cost serotonin sensor for practical routine analyses. The proposed method is potential to expand the possible applied range of the nanocomposite material for detection of various concerned electro active substances.

通过声化学和氧化聚合简单方法制备了银/聚吡咯/氧化铜（Ag / PPy / Cu ₂ O）三元纳米复合材料，其中，Ag ₂修饰Cu ₂ O，并覆盖有聚吡咯（PPy）层。所制备的材料通过紫外-可见光谱（UV-vis），FT-IR，X射线衍射（XRD），热重分析（TGA），具有EDX的扫描电子显微镜（SEM），高分辨率透射进行表征电子显微镜（HR-TEM）和X射线光电子能谱（XPS）。使用聚吡咯/玻璃碳电极（PPy / GCE），聚吡咯/氧化铜/玻璃碳电极（PPy / Cu ₂ O / GCE）和银/聚吡咯/氧化铜/玻璃碳电极（5HT）的电催化剂对5-羟色胺（5HT）的感觉进行了评估银/聚丙烯/铜₂ O / GCE）。通过循环伏安法（CV）和微分脉冲伏安法（DPV）在0.1MPBS溶液中对Ag / PPy / Cu ₂ O / GCE进行电化学处理。5-HT浓度从0.01到250 µmol L ^-1时，峰值电流响应呈线性增加，检测极限为0.0124 µmol L ^-1。它表现出高电催化活性，令人满意的重复性，稳定性，快速响应和对潜在干扰物种的良好选择性，这表明其在开发灵敏，选择性，易操作且低成本的5-羟色胺传感器用于常规常规分析方面具有潜力。所提出的方法有可能扩展纳米复合材料的可能应用范围，以检测各种有关的电活性物质。