Ochratoxins are the major components of mycotoxin that exist extensively in plant origin food. In the ochratoxins group, ochratoxin A (OTA) as the most toxic compound, which possesses a high chemical and thermal stability in foodstuff and would do harm to human beings. Hence, it is imperative to develop a simple, rapid, sensitive, robust, and accurate way to determinate OTA. Nanomaterial-based biosensors seem to be ideal analysis tools for identifying OTA on account of their tremendous merits, such as high sensitivity, excellent selectivity, simplicity of operation, and rapidity. This review focuses on the application and development of nanomaterial-enabled biosensors in OTA detection in the past years (2007-2018). Three dominant signal transduction mechanisms, i.e. optical, electrochemical, and piezoelectric, are discussed in details. Moreover, the major challenges and perspectives for future developments of OTA biosensors are also contained to provide an overview for the forthcoming research orientation.

ch曲霉毒素是真菌毒素的主要成分，广泛存在于植物来源食品中。在och曲霉毒素组中，och曲霉毒素A（OTA）是最具毒性的化合物，它在食品中具有很高的化学和热稳定性，会对人体造成伤害。因此，迫切需要开发一种简单，快速，灵敏，可靠且准确的方法来确定OTA。基于纳米材料的生物传感器具有高灵敏度，出色的选择性，操作简便和快速性等巨大优点，似乎是鉴定OTA的理想分析工具。这篇综述着眼于过去几年（2007-2018年）中纳米材料生物传感器在OTA检测中的应用和发展。三种主要的信号转导机制，即详细讨论了光学，电化学和压电。此外，还包含OTA生物传感器未来发展的主要挑战和前景，以为即将到来的研究方向提供概述。