The CNS regulates body weight; however, we still lack a clear understanding of what drives decisions about when, how much and what to eat. A vast array of peripheral signals provides information to the CNS regarding fluctuations in energy status. The CNS then integrates this information to influence acute feeding behaviour and long-term energy homeostasis. Previous paradigms have delegated the control of long-term energy homeostasis to the hypothalamus and short-term changes in feeding behaviour to the hindbrain. However, recent studies have identified target hindbrain neurocircuitry that integrates the orchestration of individual bouts of ingestion with the long-term regulation of energy balance.

中枢神经系统调节体重；然而，我们仍然缺乏对决定何时吃、吃多少和吃什么的决定因素的清晰理解。大量外围信号向 CNS 提供有关能量状态波动的信息。然后中枢神经系统整合这些信息来影响急性进食行为和长期能量稳态。以前的范式已将长期能量稳态的控制委托给下丘脑，并将摄食行为的短期变化委托给后脑。然而，最近的研究已经确定了目标后脑神经电路，它将个体摄入的协调与能量平衡的长期调节相结合。